American Journal of Medical Case Reports
ISSN (Print): 2374-2151 ISSN (Online): 2374-216X Website: Editor-in-chief: Samy, I. McFarlane
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American Journal of Medical Case Reports. 2021, 9(12), 739-742
DOI: 10.12691/ajmcr-9-12-20
Open AccessArticle

Thrombolytic Associated Pontine Hemorrhage in a Stroke Patient

Stella Onyi1, Chukwuemeka A. Umeh2, and Frederick White1

1Department of Diagnostic Radiology, Hemet Global Medical Center, California USA

2Department of Internal Medicine, Hemet Global Medical Center, California USA

Pub. Date: October 18, 2021

Cite this paper:
Stella Onyi, Chukwuemeka A. Umeh and Frederick White. Thrombolytic Associated Pontine Hemorrhage in a Stroke Patient. American Journal of Medical Case Reports. 2021; 9(12):739-742. doi: 10.12691/ajmcr-9-12-20


Stroke is a leading cause of disability and death, and the use of tissue plasminogen activator (tPA) has been shown to improve outcomes in ischemic stroke. However, despite the favorable outcome from the use of tPA, it has been associated with complications, including intracranial hemorrhage, major systemic hemorrhage, and angioedema. Though there are few reports of intracerebral hemorrhage complicating tPA use, pontine hemorrhage, a sub-set of intracerebral hemorrhage, is rarely reported. We report a case of pontine hemorrhage in an ischemic stroke patient after tPA and discussed the management of this rare complication of tPA.

stroke CVA tissue plasminogen activator pontine hemorrhage intracerebral hemorrhage

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