American Journal of Medical Case Reports
ISSN (Print): 2374-2151 ISSN (Online): 2374-216X Website: http://www.sciepub.com/journal/ajmcr Editor-in-chief: Samy, I. McFarlane
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American Journal of Medical Case Reports. 2021, 9(12), 693-697
DOI: 10.12691/ajmcr-9-12-8
Open AccessCase Study

Karyomegalic Interstitial Nephritis: Case Series and Review of Literature

Humaira Nasir1, Nida Saleem2, , Fatima Anwar1, Rabia Saleem1 and Syed Nayer Mahmud2

1Pathology Department, Shifa International Hospital, Islamabad, 00000, Pakistan

2Nephrology Department, Shifa International Hospital, Islamabad, 00000, Pakistan

Pub. Date: September 09, 2021

Cite this paper:
Humaira Nasir, Nida Saleem, Fatima Anwar, Rabia Saleem and Syed Nayer Mahmud. Karyomegalic Interstitial Nephritis: Case Series and Review of Literature. American Journal of Medical Case Reports. 2021; 9(12):693-697. doi: 10.12691/ajmcr-9-12-8

Abstract

Karyomegalic interstitial nephritis (KIN) is a rare cause of hereditary interstitial nephritis, described 45 years ago. Only about 50 cases have been described in English literature so far and none from Pakistan. This disease has an escalated course with a worsened outcome. There are a few potential mimickers of this disease both clinically and histologically, which might lead to a missed diagnosis and hence poor management. We have described here a series of 05 cases of KIN that were diagnosed at our institute for better understanding of this disease entity.

Keywords:
interstitial nephritis karyomegalic interstitial nephritis chronic kidney disease histopathology kidney transplantation

Creative CommonsThis work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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