American Journal of Medical Case Reports
ISSN (Print): 2374-2151 ISSN (Online): 2374-216X Website: Editor-in-chief: Apply for this position
Open Access
Journal Browser
American Journal of Medical Case Reports. 2021, 9(2), 134-136
DOI: 10.12691/ajmcr-9-2-9
Open AccessCase Report

Severe Dry Cough as Presenting Symptom of Patient with Five Paragangliomas

Emily Waddick1, Ameya Asarkar1, Mansour Mirfakhraee2 and Cherie-Ann O. Nathan1,

1Department of Otolaryngology/Head Neck Surgery, LSU Health, Shreveport, LA

2Department of Radiology, Willis Knighton Medical Center, Shreveport, LA

Pub. Date: December 20, 2020

Cite this paper:
Emily Waddick, Ameya Asarkar, Mansour Mirfakhraee and Cherie-Ann O. Nathan. Severe Dry Cough as Presenting Symptom of Patient with Five Paragangliomas. American Journal of Medical Case Reports. 2021; 9(2):134-136. doi: 10.12691/ajmcr-9-2-9


Introduction: A 60 year-old white female presented with a dry cough of 8 months duration. Case report: On examination, there was a reddish mass at the inferior right tympanic membrane and bilateral upper neck fullness. Subsequent imaging revealed five paragangliomas - right glomus jugulare, left glomus vagale, left carotid body tumor, right glomus vagale, and left superior mediastinum paraganglioma. Discussion: This case highlights the presenting symptoms, multidisciplinary workup, and management of a rare case of five paragangliomas.

paraganglioma parapharyngeal space tumors radiation therapy

Creative CommonsThis work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit


[1]  Darouassi Y, Alaoui M, Touati MM, et al. Carotid body tumors: a case series and review of the literature. Ann Vasc Surgery 2017; 43:265-271.
[2]  Brown ML, Zayas GE, Abel MD, et al. Mediastinal paragangliomas: the mayo clinic experience. Ann Thorac Surg 2008; 86: 946.
[3]  Erickson D, Kudva YC, Ebersold MJ, et al. Benign paragangliomas: clinical presentation and treatment outcomes in 236 patients. J Clin Endocrinol Metab 2001; 86:5210.
[4]  Boedeker CC, Neumann HP, Maier W, et al. Malignant head and neck paragangliomas in SDHB mutation carriers. Otolaryngol Head Neck Surg 2007; 137:126.
[5]  Drovdlic CM, Myers EN, Peters JA, et al. Proportion of heritable paraganglioma cases and associated clinical characteristics. Laryngoscope 2001; 111: 1822.
[6]  Harrison L, Corbridge R. Active surveillance management of head and neck paragangliomas: case series and review of the literature. Journal of Laryngology & Otology 2017; 131: 580-584.
[7]  Neumann HP, Pawlu C, Peczkowska M, et al. Distinct clinical features of paraganglioma syndromes associated with SDHB and SDHD gene mutations. JAMA 2004; 292:943.
[8]  Fishbein L, Merrill S, Fraker DL, et al. Inherited mutations in pheochromocytoma and paraganglioma: why all patients should be offered genetic testing. Ann Surg Oncol 2013; 20:1444.
[9]  Cho YY, Kwak MK, Lee SE, et al. A clinical prediction model to estimate the metastatic potential of pheochromocytoma/paraganglioma: ASES score. Surgery 2018; 4: 1-7.
[10]  Yavapolkul D and Jittreetat T. Five synchronous paragangliomas of the head and neck: a case report. J Med Assoc Thai 2016; 99: S2111-S215.
[11]  Capatina C, Ntali G, Karavitaki N, Grossman AB. The management of head-and-neck paragangliomas. Society for Endocrinology 2013; 20: 291-305.
[12]  Jackson CG, Glasscock ME 3rd, Harris PF. Glomus Tumors. Diagnosis, classification, and management of large lesions. Arch Otolaryngol 1982; 108: 401.