American Journal of Medical Case Reports
ISSN (Print): 2374-2151 ISSN (Online): 2374-216X Website: Editor-in-chief: Samy, I. McFarlane
Open Access
Journal Browser
American Journal of Medical Case Reports. 2014, 2(1), 1-3
DOI: 10.12691/ajmcr-2-1-1
Open AccessCase Report

Dosimetric Comparison between the Intensity Modulated Radiation Therapy and Volumetric Modulated arc Therapy for Prostate Cancer- A Case Study

Takeshi Hira1,

1Tohoku University, Sendai, Japan

Pub. Date: December 30, 2013

Cite this paper:
Takeshi Hira. Dosimetric Comparison between the Intensity Modulated Radiation Therapy and Volumetric Modulated arc Therapy for Prostate Cancer- A Case Study. American Journal of Medical Case Reports. 2014; 2(1):1-3. doi: 10.12691/ajmcr-2-1-1


Purpose: The main purpose of this study is to perform the dosimetric comparison between Intensity modulated radiation therapy (IMRT) and Volumetric modulated arc therapy (VMAT) for the prostate cancer by using dose-volume histograms (DVH). Methods: IMRT plan and VMAT plan were generated using 7 fields and 2 arcs, respectively, for the total dose of 76 Gy. Planning target volume (PTV) was evaluated for the maximum dose, mean dose, minimum dose, and conformity index. Rectum and bladder were evaluated for V70Gy, V50Gy, and V30Gy. The number of MUs between IMRT and VMAT plan was evaluated too. Results: The PTV dose evaluation showed that VMAT plan produced values closer to the prescription dose than did IMRT plan. The conformity index was also slightly better in VMAT plan (1.15) than in IMRT plan (1.17). The relative volume of bladder receiving radiation was always lower in VMAT plan for all parameters. However, IMRT was better than VMAT at V70Gy and V30Gy, whereas VMAT was better at V50Gy. The MUs were higher in IMRT plan (812) when compared to the one in VMAT plan (560). Conclusion: Both the VMAT and IMRT produced clinically acceptable treatment plan for the prostate cancer. Based on the single case in this study, VMAT produced slightly favorable dosimetric results.

prostate cancer treatment planning IMRT VMAT

Creative CommonsThis work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit


[1]  Teoh M, Clark CH, Wood K, Whitaker S, Nisbet A. Volumetric modulated arc therapy: A review of current literature and clinical use in practice. Br J Radiol 2011; 84: 967-96.
[2]  Otto K. Volumetric modulated arc therapy: IMRT in a single gantry arc. Med Phys 2008; 35: 310-17.
[3]  Rao M, Yang W, Chen F, Sheng K, Ye J, Mehta V, Shepard D, Cao D. Comparison of Elekta VMAT with helical tomotherapy and fixed field IMRT: plan quality, delivery efficiency and accuracy. Med Phys 2010;37(3):1350-9.
[4]  Kjaer-Kristoffersen F, Ohlhues L, Medin J, Korreman S. RapidArc volumetric modulated therapy planning for prostate cancer patients. Acta Oncol. 2009;48(2):227-32.
[5]  Yoo S, Wu QJ, Lee WR, Yin FF. Radiotherapy treatment plans with RapidArc for prostate cancer involving seminal vesicles and lymph nodes. Int J Radiat Oncol Biol Phys. 2010;76(3):935-42.
[6]  Sze HC, Lee MC, Hung WM, Yau TK, Lee AW. RapidArc radiotherapy planning for prostate cancer: Single-arc and double-arc techniques vs. intensity-modulated radiotherapy. Med Dosim 2012;37:87-91.
[7]  Wolff D, Stieler F, Welzel G, Lorenz F, Abo-Madyan Y, Mai S, Herskind C, Polednik M, Steil V, Wenz F, Lohr F. Volumetric modulated arc therapy (VMAT) vs. serial tomotherapy, step-and-shoot IMRT and 3D-conformal RT for treatment of prostate cancer. Radiother Oncol. 2009;93(2):226-33.
[8]  Zhang P, Happersett L, Hunt M, Jackson A, Zelefsky M, Mageras G. Volumetric modulated arc therapy: planning and evaluation for prostate cancer cases. Int J Radiat Oncol Biol Phys. 2010;76(5):1456-62.
[9]  Guckenberger M, Richter A, Krieger T, Wilbert J, Baier K, Flentje M. Is a single arc sufficient in volumetric-modulated arc therapy (VMAT) for complex-shaped target volumes? Radiother Oncol 2009;93:259-65.
[10]  Tsai CL, Wu JK, Chao HL, Tsai YC, Cheng JC. Treatment and dosimetric advantages between VMAT, IMRT, and helical tomotherapy in prostate cancer. Med Dosim. 2011; 36(3):264-71.
[11]  Rana S. Intensity modulated radiation therapy versus volumetric intensity modulated arc therapy. Jrnl of Medical Radiation Scie 2013; 60: 81-83.
[12]  Lu L. Dose calculation algorithms in external beam photon radiation therapy. Int J Cancer Ther Oncol 2013; 1:01025.
[13]  Oyewale S. Dose prediction accuracy of collapsed cone convolution superposition algorithm in a multi-layer inhomogenous phantom. Int J Cancer Ther Oncol 2013; 1:01016.
[14]  Rana S, Cheng C. Feasibility of the partial-single arc technique in RapidArc planning for prostate cancer treatment. Chin J Cancer. 2013; 32:546-52.
[15]  Rana S, Rogers K. Dosimetric evaluation of Acuros XB dose calculation algorithm with measurements in predicting doses beyond different air gap thickness for smaller and larger field sizes. J Med Phys 2013; 38:9-14.
[16]  Hawke S, Torrance A, Tremethick L. Evaluation of planned dosimetry when beam energies are substituted for a fraction of the treatment course. Int J Cancer Ther Oncol 2013; 1:01014.
[17]  Pokharel S. Dosimetric impact of mixed-energy volumetric modulated arc therapy plans for high-risk prostate cancer. Int J Cancer Ther Oncol 2013; 1:01011.