American Journal of Medical Case Reports
ISSN (Print): 2374-2151 ISSN (Online): 2374-216X Website: Editor-in-chief: Samy, I. McFarlane
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American Journal of Medical Case Reports. 2020, 8(10), 361-362
DOI: 10.12691/ajmcr-8-10-10
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Spontaneous Tumor Lysis Syndrome in Myeloproliferative Disorder: A Rarely Reported Clinical Entity

Sadaquat Liaqat1, Asghar Marwat1 and Munawwar Hussain1,

1Department of Internal Medicine, Conemaugh Health System, Johnstown PA 15905, USA

Pub. Date: July 03, 2020

Cite this paper:
Sadaquat Liaqat, Asghar Marwat and Munawwar Hussain. Spontaneous Tumor Lysis Syndrome in Myeloproliferative Disorder: A Rarely Reported Clinical Entity. American Journal of Medical Case Reports. 2020; 8(10):361-362. doi: 10.12691/ajmcr-8-10-10


Tumor lysis syndrome (TLS) is an oncologic emergency resulting from a massive breakdown of tumor cells. It causes electrolyte imbalance and acute renal failure. It occurs after the initiation of chemotherapy. Spontaneous tumor lysis syndrome is seen in Burkitt's lymphoma, acute lymphoid leukemia, diffuse large B-cell lymphoma, and solid tumors like breast and prostate cancer. Spontaneous tumor lysis syndrome is exceedingly rare in patients with myeloproliferative disorders. We report a rare case of spontaneous tumor lysis in an 82-year-old female patient with a myeloproliferative disorder.

tumor lysis myeloproliferative spontaneous

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