American Journal of Medical Case Reports
ISSN (Print): 2374-2151 ISSN (Online): 2374-216X Website: Editor-in-chief: Samy, I. McFarlane
Open Access
Journal Browser
American Journal of Medical Case Reports. 2020, 8(10), 358-360
DOI: 10.12691/ajmcr-8-10-9
Open AccessCase Report

Increasing Cardiac Biomarkers in the Setting of Strenuous Exercise

Sana Ahmad1, and William Chang1

1Lenox Hill Hospital, Department of Internal Medicine, New York, NY, 10075

Pub. Date: July 03, 2020

Cite this paper:
Sana Ahmad and William Chang. Increasing Cardiac Biomarkers in the Setting of Strenuous Exercise. American Journal of Medical Case Reports. 2020; 8(10):358-360. doi: 10.12691/ajmcr-8-10-9


Exercise is recommended for both primary and secondary prevention of cardiovascular disease. Exercise-associated elevations of cardiac biomarkers can be present especially after prolonged and strenuous endurance exercise bouts but the exact mechanism and clinical significance is unclear [1]. This case report is of a patient with recent increase in exercise activity who presented to the emergency department with atypical symptoms and increasing cardiac biomarkers concerning for myocardial infarction. He was admitted and taken for left heart catheterization which showed non-obstructive coronary artery disease. The lack of awareness of this phenomenon may lead to inappropriate management of these patients.

Exercise-induced troponin elevation cardiac biomarkers strenuous exercise troponinemia cardiovascular health

Creative CommonsThis work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit


[1]  Scharhag J, , , , , “Exercise-associated increases in cardiac biomarkers,” Medicine & Science in Sports & Exercise, 40(8), 1408-15, Aug 2008.
[2]  Shave R, Baggish A, George K, Wood M, Scharhag J, Whyte G, Gaze D, Thompson P, “Exercise- Induced Cardiac Troponin Elevation,” Journal of the American College of Cardiology, 56(3); 169-75, Jul 2010.
[3]  López-López S, Pareja-Galeano H, “Cardiovascular biomarkers modified by exercise,” Journal of Laboratory and Precision Medicine, 3(2), 17, Feb 2018.
[4]  Baker P, Leckie T, Harrington D, Richardson A, “Exercise-induced cardiac troponin elevation: An update on the evidence, mechanism and implications,” , 22, 181-186, March 2019.
[5]  Al-Hadi H, Fox K, “Cardiac Markers in the Early Diagnosis and Management of Patients with Acute Coronary Syndrome,” , 9(3), 231-246, Dec 2009.
[6]  Peretti A, Mauri L, Masarin A. et al, “Cardiac Biomarkers Release in Preadolescent Athletes After an High Intensity Exercise,” High Blood Press Cardiovasc Prev, 25(1), 89-96, March 2018
[7]  Eijsvogels TM, , , , , “Exercise-Induced Cardiac Troponin Release: Real-Life Clinical Confusion,” Current Medicinal Chemistry, 18(23), 3457-61, 2011.