American Journal of Medical Case Reports
ISSN (Print): 2374-2151 ISSN (Online): 2374-216X Website: Editor-in-chief: Samy, I. McFarlane
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American Journal of Medical Case Reports. 2020, 8(7), 187-188
DOI: 10.12691/ajmcr-8-7-7
Open AccessCase Report

A Case of Invasive Mucinous Adenocarcinoma of the Appendix

Richmond Laryea1, , Aazim Arif1 and Aja Adams1

1Florida State College of Medicine, Ft. Pierce Campus, Ft. Pierce, FL USA

Pub. Date: April 17, 2020

Cite this paper:
Richmond Laryea, Aazim Arif and Aja Adams. A Case of Invasive Mucinous Adenocarcinoma of the Appendix. American Journal of Medical Case Reports. 2020; 8(7):187-188. doi: 10.12691/ajmcr-8-7-7


Background: Although mucinous neoplasms are primarily found within the colon, there are rare instances in which these tumors arise from within the appendix. The appendix is a small blind pouch located at the beginning of the large colon. The incidence of primary appendicular mucoceles found in appendectomies is a rare occurrence, common in those over 50. These tumors often present with the symptoms of appendicitis. Of the appendiceal tumors, invasive mucinous appendicular carcinoma is rare subtype. If improperly managed, this malignancy may present with adverse tumor burden outcomes upon local invasion. Case Presentation: An 83-year-old male with a past medical history of GERD and hyperlipidemia presented with clinical symptoms of appendicitis. CT imaging of the abdomen was consistent with a distended appendix, also consistent with appendicitis. However, upon excision of the appendix, pathology revealed a rare occurrence of primary mucinous adenocarcinoma of the appendix. Conclusion: We present a case of primary mucinous adenocarcinoma of the appendix successfully managed with urgent surgical removal. Given the vague presentation of mucinous adenocarcinoma of the appendix prior to appendiceal rupture and local metastasis, this case demonstrates the importance of a surgical approach regarding appendicitis in the elderly population, rather than medical treatment.

mucinous adenocarcinoma appendix

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[1]  Tirumani SH, Fraser-Hill M, Auer R, Shabana W, Walsh C, Lee F, Ryan JG. Mucinous neoplasms of the appendix: a current comprehensive clinicopathologic and imaging review. Cancer Imaging. 2013 Feb 22; 13(1): 14-25.
[2]  Panarelli NC, Yantiss RK. Mucinous neoplasms of the appendix and peritoneum. Arch Pathol Lab Med. 2011; 135: 1261-1268. PMid :21970481.
[3]  Ronnett, B.M., Yan, H., Kurman, R.J., Shmookler, B.M., Wu, L. and Sugarbaker, P.H. (2001), Patients with pseudomyxoma peritonei associated with disseminated peritoneal adenomucinosis have a significantly more favorable prognosis than patients with peritoneal mucinous carcinomatosis. Cancer, 92: 85-91.
[4]  Benedix F, Reimer A, Gastinger I, Mroczkowski P, Lippert H, Kube R. Primary appendiceal carcinoma-epidemiology, surgery and survival: results of a German multi-center study. Study Group Colon/Rectum Carcinoma Primary Tumor. Eur J SurgOncol. 2010; 36(8): 763
[5]  Hananel, N., Powsner, E. and Wolloch, Y. (1998), Adenocarcinoma of the appendix: an unusual disease. Eur J Surg, 164: 859-862.
[6]  Andersson A, Bergdahl L, Boquist L. Primary carcinoma of the appendix. Ann Surg. 1976 Jan; 183(1): 53-7.
[7]  Anania G, Giaccari S, Solfrini G, Scagliarini L, Vedana L, Resta G. Appendicular mucocele: two case reports and literature review. G Chir. 2015 Nov-Dec; 36(6): 276-9.
[8]  Miner TJ, Shia J, Jaques DP, Klimstra DS, Brennan MF, Coit DG. Long-term survival following treatment of pseudomyxoma peritonei: an analysis of surgical therapy. Ann Surg. 2005 Feb; 241(2): 300-8.
[9]  Köhler, F., Rosenfeldt, M., Matthes, N. et al. Zufallsbefund muzinöse Neoplasie der Appendix. Chirurg 90, 194-201 (2019).
[10]  Luo C, Cen S, Ding G, Wu W. Mucinous colorectal adenocarcinoma: clinical pathology and treatment options. Cancer Commun (Lond). 2019 Mar 29; 39(1): 13.
[11]  Connor, S.J., Hanna, G.B. & Frizelle, F.A. Appendiceal tumors. Dis Colon Rectum 41, 75-80 (1998).