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American Journal of Medical Case Reports. 2020, 8(5), 128-133
DOI: 10.12691/ajmcr-8-5-5
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HIV-associated Extracranial Arterial Aneurysms: A Systematic Review

Pramod Theetha Kariyanna1, Jessica Yager2, Louis Salciccioli1, Jason. M. Lazar1, David John Polman3, Harshith Priyan Chandrakumar3 and Isabel M. McFarlane3,

1Division of Cardiovascular Diseases, State University of New York- Downstate Health Science University, Brooklyn, NY, USA- 11203

2Infectious Disease, State University of New York- Downstate Health Science University, Brooklyn, NY, USA- 11203

3Internal Medicine, State University of New York- Downstate Health Science University, Brooklyn, NY, USA- 11203

Pub. Date: March 19, 2020

Cite this paper:
Pramod Theetha Kariyanna, Jessica Yager, Louis Salciccioli, Jason. M. Lazar, David John Polman, Harshith Priyan Chandrakumar and Isabel M. McFarlane. HIV-associated Extracranial Arterial Aneurysms: A Systematic Review. American Journal of Medical Case Reports. 2020; 8(5):128-133. doi: 10.12691/ajmcr-8-5-5


Human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) has been found to be associated with an increased risk of cardiovascular disease, and the development of arterial aneurysms in particular, intracranial aneurysms. In this review, we will review the reported HIV-associated extracranial aneurysms (HECAA) and their possible association with HIV/AIDS. We will discuss the proposed pathogenetic pathways leading to arterial aneurysms. HECAA, a subset of HIV/AIDS-associated arterial aneurysm (HAA), is more commonly seen in the adult population and in those with lower CD4+ T-cell counts and higher HIV viral loads. There also appears to be an advantage to early diagnosis of HECAA. There are viable treatment options available, as 61.4% of patients with HECAA underwent a corrective procedure. Furthermore, the mortality rate of 1.75% in HECAA was much lower when compared to HICAA.

HIV AIDS aneurysm arteriopathy cardiovascular disease

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