American Journal of Medical Case Reports
ISSN (Print): 2374-2151 ISSN (Online): 2374-216X Website: Editor-in-chief: Samy, I. McFarlane
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American Journal of Medical Case Reports. 2019, 7(11), 289-291
DOI: 10.12691/ajmcr-7-11-7
Open AccessCase Report

Adalimumab Induced Aseptic Meningitis and Focal Partial Seizures in Patient with Crohn’s Disease

Corey S. Ellis1, Hayden L. Smith1, and Lisa A Veach2

1Graduate Medical Education, UnityPoint Health-Des Moines, Des Moines, United States

2UnityPoint Clinic Multi-Specialty-Infectious Disease, UnityPoint Health, Des Moines, United States

Pub. Date: September 01, 2019

Cite this paper:
Corey S. Ellis, Hayden L. Smith and Lisa A Veach. Adalimumab Induced Aseptic Meningitis and Focal Partial Seizures in Patient with Crohn’s Disease. American Journal of Medical Case Reports. 2019; 7(11):289-291. doi: 10.12691/ajmcr-7-11-7


Tumor necrosis factor α inhibitors (TNFα-i) are a commonly prescribed class of medications for the treatment of inflammatory bowel disease. With the increasing use of this medication class, some uncommon adverse effects have been reported. We present a case of a young male recently prescribed adalimumab for Crohn’s disease who developed aseptic meningitis with associated focal partial seizures.

anti-inflammatory agents/adverse effects crohn disease/drug therapy adalimumab meningitis aseptic/chemically induced meningitis aseptic/drug therapy

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