American Journal of Medical and Biological Research
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American Journal of Medical and Biological Research. 2017, 5(2), 23-30
DOI: 10.12691/ajmbr-5-2-3
Open AccessArticle

To Estimate Pulmonary Arterial Compliance and Pulse Wave Velocity in Cerebral-Cardiovascular Patients Using CT Cardiac Images

WeiChih Hu1, , Hsuan-Ming Tsao2, Jian Xiang Zhi2, Harmon Chris T. Herman3, Lemmuel L. Tayo3, Yashbir Singh1, Kathiravan S4, João Manuel R.S. Tavares5 and Chandan Chakraborty6

1Department of Biomedical Engineering, Chung Yang Christian University, Chung Li, Taiwan

2Divisions of Cardiology, National Yang Ming University Hospital and National Yang Ming University, Yi-Lan, Taiwan

3Mapua Institute of Technology, Manila, Philippines

4Department of Computer Science and Information Engineering, National Ilan University, Taiwan

5Instituto de Ciência e Inovação em Engenharia Mecânica e Engenharia Industrial, Departamento de Engenharia Mecânica, Faculdade de Engenharia, Universidade do Porto, Portugal

6School of Medical Science & Technology (SMST), Indian Institute of Technology Kharagpur, India

Pub. Date: November 22, 2017

Cite this paper:
WeiChih Hu, Hsuan-Ming Tsao, Jian Xiang Zhi, Harmon Chris T. Herman, Lemmuel L. Tayo, Yashbir Singh, Kathiravan S, João Manuel R.S. Tavares and Chandan Chakraborty. To Estimate Pulmonary Arterial Compliance and Pulse Wave Velocity in Cerebral-Cardiovascular Patients Using CT Cardiac Images. American Journal of Medical and Biological Research. 2017; 5(2):23-30. doi: 10.12691/ajmbr-5-2-3

Abstract

Arterial stiffness has been proven to be one of the most promising diagnostic and prognostic features of many cardiovascular diseases (CVD). Arterial compliance (AC) and pulse wave velocity (PWV) allows a good quantitative assessment of arterial stiffness. To estimate pulmonary Arterial Compliance and Pulse Wave Velocity in Cerebral-Cardiovascular Patients using 64-Row Multi-Detector Computed Tomography Cardiac Images. Here in this work, we have used an in house developed three-dimensional reconstruction algorithm that extracts high-resolution cardiac Computer Tomography images in Digital Imaging and Communications in Medicine (DICOM) format from nine subjects. The subjects consist four patients with stroke (SR) turned to atrial fibrillation (AF) and five patients with both SR and AF. The calculation showed strok volume of Left and Right Ventricles, which are near equal to 62.56±12.61 ml and 65.95±13.13 ml, respectively, with a good positive correlation (R = 0.717, p < 0.0001) while pulse wave velocity and arterial compliance are calculated to be 0.21±0.0665 m/s and 0.09 ± 0.0547 ml/mmHg for patients with SR turned AF, 0.15±0.0502 m/s and 0.10 ± 0.0438 for the SR and AF patients. We concluded that the derived methodology for calculation of PWV and AC from 3D cardiac CT images could be used as an index in the evaluation of arterial stiffness.

Keywords:
arterial compliance arterial stiffness Computer Tomography Digital Imaging Cardiac stroke

Creative CommonsThis work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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References:

[1]  Babin, D., Devos, D., Pizurica, A., Westenberg, J. et al. Robust segmentation methods with application to aortic pulse wave velocity calculation. Computerized Medical Imaging and Graphics, 2013, 179-189.
 
[2]  Cabrera, S.R.M., Lucas, C.T., Ruiz, S.G. et al. Relation between atrial fibrillation and pulse wave velocity in hypertensive patients. The Journal of Clinical Hypertension, 2012, 14 Suppl 1:151.
 
[3]  Fielden, S.W., Fornwalt B.K., Jerosch-Herold, M., et al. A new method for the determination of aortic pulse wave velocity using cross-correlation on 2D PCMR velocity data. J Magn Reson Imaging, 2008, 27, 1382-1387.
 
[4]  Horvath, I., Lenkey, Z., Alessandri N., Tufano, F., Kis, P., et al. Invasive validation of a new oscillometric device (arteriography) for measuring augmentation index, central blood pressure and aortic pulse wave velocity. Journal of Hypertension; 2010,28(10): 2068-75.
 
[5]  Gasecki, D., Rojek, A., Kwarciany, M., Kowalczyk, K., et al. Pulse wave velocity is associated with early clinical outcome after ischemic stroke. Atherosclerosis, 2012, 348-352.
 
[6]  Ohnesorge, B.M., Becker, C.R., et al. Multi-slice CT in Cardiac Imaging. New York, NY: Springer-Verlag Berlin Heidelberg, 2002.
 
[7]  Graham, R.N.J., Perriss, R.W., Scarsbook, A.F. DICOM demystified: A review of digital file formats and their use in radiological practice. Clinical Radiology, 2005,60, 1133-1140.
 
[8]  Adams, R., Bischof, Leanne. Seeded region growing. IEEE Transactions on Pattern Analysis and Machine Intelligence, 1994, Vol. 16, 641-647.
 
[9]  Chang, S.L., Tai, C.T., Lin, Y.J., et al. The role of left atrial muscular bundles in catheter ablation of atrial fibrillation. J Am Coll Cardiol , 2007, 50: 964-973.
 
[10]  Tsao, H.M., Hu, W.C., Wu, M.H., et al. Quantitative analysis of quantity and distribution of epicardial adipose tissue surrounding the left atrium in patients with atrial fibrillation and effect of recurrence after ablation. Am J Cardiol, 2011, 107: 1498-1503.
 
[11]  Ohnesorge, B.M., Becker, C.R., Flohr, T.G., Reiser, M.F. Multi-slice CT in Cardiac Imaging. New York, NY: Springer-Verlag Berlin Heidelberg, 2002.
 
[12]  Tsao, H.M., Hu, W.C., Wu, M.H., Tai, C.T., et al. The impact of catheter ablation on the dynamic function of the left atrium in patients with atrial fibrillation: insights from four-dimensional computed tomographic images. J Cardiovasc Electrophysiol. 2010, 21: 270-277.
 
[13]  Gatehouse, P.D., Keegan J., Crowe, L.A., et al. Applications of phase-contrast flow and velocity imaging in cardiovascular MRI. European Radiology, 2005, 15(10); 2172-84.
 
[14]  Ibrahim, E.S., Johnson, K., Miller A., White, R. Measuring aortic pulse wave velocity using high-field cardiovascular magnetic resonance: comparison of techniques. Journal of Cardiovascular Magnetic Resonance; 2010, 12 (1), 26-26.
 
[15]  Pannier, B.M., Avolio, A.P., et al. Methods and devices for measuring arterial compliance in humans. American Journal of Hypertension, 2002, 15: 743-753.
 
[16]  Canadas, V., Vilacosta, I., Luaces, M., Bustos, A. et al. Thrombosis in an apparently normal thoracic aorta and arterial embolism. Revista Espanola de Cardiologia. 2008, Vol. 6, 196-200.
 
[17]  Spencer, M.P., Denison, A.B. Jr..Pulsatile blood flow in the vascular system. Handbook of Physiology. Circulation. II Am. Physiol. SocWashington, DC, 1963, chapt. 25, p. 842.
 
[18]  Cullington, D., Goode, K.M., Zhang, J., et al. Is heart rate important for patients with heart failure in atrial fibrillation? JACC: heart Failure, 2014, Vol. 2, 213-220.
 
[19]  Halliburton, S., Arbab-Zadeh, A., Dey, et al. State-of-the-art in CT hardware and scan modes for cardiovascular CT. Journal of Cardiovascular Computed Tomography, 2012, 6, 154-163.
 
[20]  Kass, M., Witkin A., Terzopoulos, D. Snakes: Active Contour Models. International Journal of Computer Vision, 1998, 323-331.
 
[21]  Lim, H.S., and Lip, G.Y.H. Arterial stiffness: beyond pulse wave velocity and its measurement. Journal of Human Hypertension, 2008, 656-658.
 
[22]  Parisi, A.F., Moynihan, P.F., Feldman, C.L., Folland, E.D. Approacehs to determination of left ventricular volume ejection fraction by real-time twodimensional echochardiography. Clin. Cardiol, 1979, 2, 257-263.
 
[23]  Vulliemoz, S., Stergiopulos, N., Meuli, R. Estimation of local aortic elastic properties with MRI. Magn Reson Med., 2002, 47, 649-654.