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American Journal of Medical and Biological Research. 2013, 1(4), 159-164
DOI: 10.12691/ajmbr-1-4-9
Open AccessReview Article

Complicated Skin and Skin Structure Infections (cSSSI’s): A Comprehensive Review

K V Ramana1, , Venkata BharatKumar Pinnelli2, Bhanu Prakash3, Wilma Delphine Silvia CR4, Sabitha Kandi5, CH V Sharada6, Anand Kalaskar1, Sanjeev D Rao1, Ratna Mani7 and Ratna Rao7

1Department of Microbiology, Prathima Institute of Medical Sciences, Karimnagar, India

2Department of Biochemistry, Vydehi Institute of Medical Sciences and Research Centre, Bangalore, India

3Department of Dermatology, Vydehi Institute of Medical Sciences and Research Centre, Bangalore, India

4Department of Biochemistry, Akash Institute of Medical Sciences & Research Center, Bangalore, India

5Department of Biochemistry, Chalmeda Anandarao Institute of Medical Sciences, Karimnagar, India

6Department of Microbiology, Prime Hospitals, Hyderabad, India

7Department of Microbiology, Apollo Hospitals, Jubilee Hills, Hyderabad, India

Pub. Date: December 24, 2013

Cite this paper:
K V Ramana, Venkata BharatKumar Pinnelli, Bhanu Prakash, Wilma Delphine Silvia CR, Sabitha Kandi, CH V Sharada, Anand Kalaskar, Sanjeev D Rao, Ratna Mani and Ratna Rao. Complicated Skin and Skin Structure Infections (cSSSI’s): A Comprehensive Review. American Journal of Medical and Biological Research. 2013; 1(4):159-164. doi: 10.12691/ajmbr-1-4-9


Complicated skin and skin structure infections (cSSSI’s) are among the most common microbial infections occurring both in the community and the hospitals. Aetiology of cSSSI’s is complex and includes various microorganisms (bacteria, fungi, parasites and viruses). cSSSI’s in general are poly microbial in nature including both anaerobic and aerobic bacterial species. Primary cSSSI’s resulting from single bacterial species and secondary bacterial infections in patients suffering from skin conditions due to autoimmune conditions (eczema) or other microbial causes (viruses, fungi and parasites) have been reported in the literature. Occurrence of multi-drug resistant bacteria, underlying co-morbidities contribute to the complications in the management of cSSSI’s. Formulating effective guidelines for clinical, laboratory diagnosis, treatment and management of patients suffering from cSSSI’s would certainly be beneficial in the reduction of morbidity and mortality.

complicated skin and skin structure infections (cSSSI’s) aetiology of cSSSI’s multi-drug resistance

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