American Journal of Infectious Diseases and Microbiology
ISSN (Print): 2328-4056 ISSN (Online): 2328-4064 Website: http://www.sciepub.com/journal/ajidm Editor-in-chief: Maysaa El Sayed Zaki
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American Journal of Infectious Diseases and Microbiology. 2017, 5(2), 80-86
DOI: 10.12691/ajidm-5-2-2
Open AccessArticle

Detection of Nocardia from Chronic Skin and Lung Infections in Bangladeshi Patients

Afzalunnessa Binte Lutfor1, , Ritu Saha1, Arpita Deb1, Asif Mujtaba Mahmud2, Abu Ahmed Ashraf Ali1, Tasmin Haque1, Sadia Rahman1, Nadia Sharmin Shorno3 and Amina Arafat1

1Department of Microbiology, Ad-din Women’s Medical College Hospital, Dhaka, Bangladesh

2Department of Respiratory Medicine, Asgar Ali Hospital, Dhaka, Bangladesh

3Department of Critical care & Emergency Medicine, Dhaka Medical College Hospital, Dhaka, Bangladesh

Pub. Date: May 10, 2017

Cite this paper:
Afzalunnessa Binte Lutfor, Ritu Saha, Arpita Deb, Asif Mujtaba Mahmud, Abu Ahmed Ashraf Ali, Tasmin Haque, Sadia Rahman, Nadia Sharmin Shorno and Amina Arafat. Detection of Nocardia from Chronic Skin and Lung Infections in Bangladeshi Patients. American Journal of Infectious Diseases and Microbiology. 2017; 5(2):80-86. doi: 10.12691/ajidm-5-2-2

Abstract

Nocardiosis is an acute or chronic infectious disease that may occur in cutaneous, pulmonary and disseminated form in both immunocompromised and immunocompetent host. It may become potentially severe due to delayed diagnosis and incomplete or ineffective treatment. So the aim of the study was to isolate Nocardia spp. from suspected samples, mainly from chronic unhealed wounds and to identify appropriate antimicrobials by susceptibility testing in Bangladeshi patients. Methods: From January 2015-2017, 62 samples were collected which were studied for Nocardial identification and susceptibility testing. Results: Out of total 62 cases, 18 (29.03%) cases were Nocardia positive cases. Besides 6 Acinetobacter spp. and 2 Actinomyces spp. with other varied pathogens were isolated. Among 18 identified nocardiosis patients, majority (10) were post surgery cases, 6 suspected skin and glandular tuberculosis (TB) cases, one had breast sinus, and one was suspected pulmonary TB case. In terms of susceptibility of nocardial isolates, 100% were susceptible to linezolid, 88.9% to amikacin and 78% to trimethoprim-sulphamethoxazole.

Keywords:
chronic skin infection discharging sinus Nocardia non healing wound primary cutaneous nocardiosis

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