American Journal of Infectious Diseases and Microbiology
ISSN (Print): 2328-4056 ISSN (Online): 2328-4064 Website: http://www.sciepub.com/journal/ajidm Editor-in-chief: Maysaa El Sayed Zaki
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American Journal of Infectious Diseases and Microbiology. 2015, 3(1), 1-5
DOI: 10.12691/ajidm-3-1-1
Open AccessArticle

Prevalence of Malaria in Patients Attending the General Hospital Makarfi, Makarfi Kaduna – State, North-Western Nigeria

Millicent Ladi Umaru1, and Gabriel Noblefather Uyaiabasi2

1Department of Pharmacology & Toxicology, Faculty of Pharmaceutical Sciences, Usmanu Danfodiyo University, Sokoto, Nigeria

2Department of Pharmacology, Therapeutics and Toxicology, College of Medicine, University of Lagos, Lagos, Nigeria

Pub. Date: January 25, 2015

Cite this paper:
Millicent Ladi Umaru and Gabriel Noblefather Uyaiabasi. Prevalence of Malaria in Patients Attending the General Hospital Makarfi, Makarfi Kaduna – State, North-Western Nigeria. American Journal of Infectious Diseases and Microbiology. 2015; 3(1):1-5. doi: 10.12691/ajidm-3-1-1

Abstract

Nigeria is a high endemic country for malaria. Its large population, diverse weather conditions and cultures make it a bit difficult implementing the same malaria control measures throughout the country. Prevalence studies are therefore essential for better understanding and implementation of intervention programs. This study determined some malariometric parameters such as malaria prevalence, transmission based on age and gender, parasite density, fever and anaemia in patients attending General Hospital Makarfi, during the malaria transmission season. All participants were screened microscopically for malaria and classified into 3 groups: under 5 years, 5 – 15 years and above 15. A total of 1173 participants were screened out of which 419 (35.7%) were positive. The geometric mean parasite density was 15,108 parasite/µL of blood. Children aged 5 – 15 years had a statistically significant higher infection rate compared to the other groups. Males were more prone to malaria than females. Presence of parasitaemia, fever or anaemia did not correlate with the presence of malaria. Some of the positive patients had high parasite densities and yet asymptomatic. More malariometric surveys are needed in Nigeria in order to adopt control efforts that best suit rural areas and smaller communities especially during peak malaria transmission season.

Keywords:
Malaria Plasmodium falciparum artemisinin combination therapy and prevalence

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References:

[1]  World Health Organization, “World Malaria Report 2013”, World Health Organization, Geneva, Switzerland, Dec. 2013.
 
[2]  National Population Commission (NPC) [Nigeria], “ICF Macro: Nigeria Demographic and Health Survey 2008”, Abuja, Nigeria: NPC and ICF Macro; 2009
 
[3]  Noland, G.S, Graves, P.M,SallauA, Eigege, A, Emukah, E, Patterson, A.E, et al. “Malaria prevalence, anemia and baseline intervention coverage prior to mass net distribution in Abia and Plateau States, Nigeria”, BMC Infectious Diseases, 14: 168. Mar. 2014.
 
[4]  Federal Ministry of Health (FMOH), “Technical Report of Drug Efficacy Studies 2009-2010”, Federal Ministry of Health Abuja-Nigeria, 2010.
 
[5]  Federal Ministry of Health (FMOH), “Strategic Plan for Malaria Control in Nigeria 2009-2013”, Federal Ministry of Health Abuja, Nigeria: 2008.
 
[6]  Aina, O.O, Agomo,C.O, Olukosi, Y.A, Okoh, H.I, Iwalokun, B.A, EgbunaK.N, et al. “Malariometric survey of Ibeshe community in Ikorodu, Lagos state: dry season”, Malaria Research and Treatment, 487250. May 2013.
 
[7]  World Health Organization, “Methods for surveillance of antimalarial drug efficacy”, World Health Organization, Switzerland, 2009.
 
[8]  Udoh,E.E, Oyo-ita,A.E, Odey, F.A,EyongK.I, OringanjeC.M, OduwoleO.A, et al. “Malariometric Indices among Nigerian children in a rural setting”, Malaria Research and Treatment, 716805. Feb. 2013.
 
[9]  Mawili-Mboumba, D.P, Akotet, M.K.B, Kendjo, E, Nzamba, J, Medang, M.O, MbinaJ.M, Kombila M, MCORU team, “Increase in malaria prevalence and age of at risk population in different areas of Gabon”, Malaria Journal, 12:3. Jan, 2013.
 
[10]  World Health Organization, “Global report on antimalarial drug efficacy and drug resistance, 2000-2010”, World Health Organization, Geneva, Switzerland”, 2010.
 
[11]  Happi, C.T, Gbotosho, G.O, FolarinO.A, Sowunmi, A, Hudson, T, O’Neil, M, Milhous, W, Wirth, D.F, Oduola, A.M.J, “Selection of Plasmodium falciparum multi-drug resistance gene 1 alleles in asexual stages and gametocytes by artemether-lumefantrine in Nigerian children with uncomplicated falciparum malaria” Antimicrobial Agents and Chemotherapy, 53: 888-895. Mar. 2009.
 
[12]  Federal Ministry of Health (FMOH), “National Antimalarial Treatment Policy, Federal Ministry of Health Nigeria”, National Malaria and Vector Control Division, Abuja, Nigeria, 2005.
 
[13]  FaladeC.O, OgundeleA.O, Yusuf B.O, AdemowoO.G,Ladipo, S.M, “High efficacy of two artemisinin-based combinations (artemether-lumefantrine and artesunate plus amodiaquine) for acute uncomplicated malaria in Ibadan, Nigeria”, Tropical Medicine & International Health, 13:635-643. May 2008.
 
[14]  Sowunmi, A, Gbotosho, G.O, Happi, C.T, Adedeji, A.A, Fehintola, F.A, Folarin, O.A, Tambo, E, Fateye, B.A, “Therapeutic efficacy and effects of artemether-lumefantrine and amodiaquinesulfalene-pyrimethamine on gametocyte carriage in children with uncomplicated Plasmodium falciparum malaria in southwestern Nigeria”, American Journal Tropical Medical Hygiene, 77: 235-241. Apr. 2007.
 
[15]  Sowunmi, A, GbotoshoG.O, Happi C, Okuboyejo, T, Folarin, O, Balogun, S, Michael O, “Therapeutic efficacy and effects of artesunate-mefloquine and mefloquine alone on malaria associated anaemia in children with uncomplicated Plasmodium falciparum malaria in southwest Nigeria”, American Journal Tropical Medical Hygiene, 81: 979-986. Aug. 2009.
 
[16]  Bloland,P.B, “Drug Resistance in Malaria”, World Health Organization, Switzerland”, 2001.
 
[17]  AweekaF.T, German,P.I, “Clinical Pharmacology of Artemisinin-Based Combination Therapies”, Clinical Pharmacokinetics; 47 (2): 91-1020312-5963/08/0002-0091. Feb. 2008.
 
[18]  Oresanya,O.B, Hoshen M. SofolaO.T, “Utilization of insecticide-treated nets by under-five children in Nigeria: assessing progress towards the Abuja targets” Malaria Journal, 7 (1): 145. Jul. 2008.
 
[19]  GarleyA.E,,Ivanovich E, Eckert, E, Negroustoueva, S, Ye, Y, “Gender differences in the use of insecticide-treated nets after a universal free distribution campaign in Kano State, Nigeria: post-campaign survey results”, Malaria Journal, 12 (1): 119. Apr 2013.