Large Intestine Infarction due to Mucormycosis Complicated with Acute Myeloid Leukemia. Case Report

Motoharu Shibusawa^1, , Hiroko Hidai¹, Sayuri Motomura¹, Yuuji Itou² and Hisashi Tsutsumi¹

¹Department of Hematology Medicine, Tokyo Metropolitan Health and Medical Treatment Corporation, Tama-Hokubu Medical Center

²Department of Pathology, Tokyo Metropolitan Health and Medical Treatment Corporation, Tama-Hokubu Medical Center

Cite this paper:
Motoharu Shibusawa, Hiroko Hidai, Sayuri Motomura, Yuuji Itou and Hisashi Tsutsumi. Large Intestine Infarction due to Mucormycosis Complicated with Acute Myeloid Leukemia. Case Report. American Journal of Infectious Diseases and Microbiology. 2014; 2(3):51-54. doi: 10.12691/ajidm-2-3-3

Abstract

Mucormycosis is known to be fatal, and the diagnosis is difficult to be made. Gastrointestinal mucormycosis is rarely complicated with gastrointestinal infarction. We report a rare case of mucormycosis complicated with large intestine infarction. An 82-year-old man was admitted to our hospital, because of blastosis. A diagnosis of acute myeloid leukemia prior myelodysplastic syndrome was made. On the twentieth day of admission, bleeding developed in the airway secondary to thrombocytopenia and disseminated intravascular coagulation. He died due to respiratory failure and autopsy was carried out. The novel finding of the autopsy was large intestine infarction due to mucormycosis, although the clinical course did not show features suggesting gastrointestinal mucormycosis. A diagnosis of mucormycosis was made by autopsy. In the patients with risk factors including hematologic malignancies, we should pay attention to gastrointestinal mucormycosis.

Keywords:
gastrointestinal mucormycosis large intestine infarction acute myeloid leukemia

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