American Journal of Infectious Diseases and Microbiology
ISSN (Print): 2328-4056 ISSN (Online): 2328-4064 Website: http://www.sciepub.com/journal/ajidm Editor-in-chief: Maysaa El Sayed Zaki
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American Journal of Infectious Diseases and Microbiology. 2022, 10(3), 107-111
DOI: 10.12691/ajidm-10-3-4
Open AccessArticle

Extrapulmonary Tuberculosis: Prevalence and Associated Factors in the Infectious Diseases Department of the Brazzaville University Hospital

Ossibi Ibara BR1, 2, , Adoua doukaga T1, 2, Bemba ELP1, 3, Ekat M1, 2, Gboungoule S1, Angonga Pabota E1, Bendett P.1, Okemba-Okombi FH1, 3 and Ossou-Nguiet PM1, 4

1Marien Ngouabi University, Faculty of Health Sciences, Brazzaville Congo

2Infectious Diseases Department, Brazzaville University Hospital, Congo

3Pneumology Department, University Hospital of Brazzaville, Congo

4Neurology Department, University Hospital of Brazzaville, Congo

Pub. Date: August 14, 2022

Cite this paper:
Ossibi Ibara BR, Adoua doukaga T, Bemba ELP, Ekat M, Gboungoule S, Angonga Pabota E, Bendett P., Okemba-Okombi FH and Ossou-Nguiet PM. Extrapulmonary Tuberculosis: Prevalence and Associated Factors in the Infectious Diseases Department of the Brazzaville University Hospital. American Journal of Infectious Diseases and Microbiology. 2022; 10(3):107-111. doi: 10.12691/ajidm-10-3-4

Abstract

Objective: Determine the prevalence of extra-pulmonary tuberculosis in the Infectious diseases department of the University Hospital of Brazzaville and look for associated factors. Patients and method: Cross-sectional study aimed at descriptive and analytical description of cases of extra-pulmonary tuberculosis hospitalized in the infectious diseases department between 1erJanuary 2019 and June 30, 2021 (30 months)in patients infected with HIV or not, receiving treatment or nothighly active antiretroviral drug and who gave free and informed consent to participate in this study. Results: A total of 100 hospitalized patients (5.4% of admissions) mean age 44.05 ± 12.7 years [18-76], female (55%) ayahad a secondary education level (n=53; 53%), single (n=79; 79%), lived in town (93%) and infected with HIV (92.6%). The average consultation time was 41.6±10.5 [1-210] days, mainly forfever (85%) and impairedgeneral condition (63%). Tuberculosis was localized in the lymph nodes and lungs (29%), pleural (22%) and lymph nodes alone (17%). the various opportunistic infections found were CNM (n=12), cerebral toxoplasmosis (n=9). The Mean CD4 counts were 165.2 ±56.8 [2-644]. IDRT was anergic in 68.4% and GenXpert was positive in 23% of cases. Abdominal ultrasound found ADP (38%) and ascites (13%). EHRZ treatment was administered in 81% of saless and ART introduced within an average of 30.9 ± 7.7 days. It wasmainly from the TDF+FTC+EFV combination in 36% of cases. The mean hospital stay was 17.8±14 [1-90] days. The overall lethality was 51% (n=51) due to anemic shock (n=17; 33.3%) and septic (n=12; 23.5%). Age (p=0.03), being single (p=0.02), meningeal syndrome (p=0.006) and coma (p=0.02) were related to the occurrence of death. Conclusion: The hospital prevalence of tuberculosis extrapulmonary is high in the infectious diseases department of the CHUB as is the lethality, despite early treatment. Age and neurological location influence the prognosis, which is to say the importance of prevention.

Keywords:
tuberculosis extra pulmonary prevalence CHU-Brazzaville

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