American Journal of Infectious Diseases and Microbiology
ISSN (Print): 2328-4056 ISSN (Online): 2328-4064 Website: Editor-in-chief: Maysaa El Sayed Zaki
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American Journal of Infectious Diseases and Microbiology. 2020, 8(4), 146-148
DOI: 10.12691/ajidm-8-4-5
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Varicella Zoster Infection Complicated by Acute Disseminated Encephalomyelitis and Pneumonitis in an Immunocompetent Patient

Assaf Potruch1, and Yuval Ishay1

1Department of internal medicine, Hebrew University-Hadassah Medical Center, Jerusalem, Israel

Pub. Date: December 14, 2020

Cite this paper:
Assaf Potruch and Yuval Ishay. Varicella Zoster Infection Complicated by Acute Disseminated Encephalomyelitis and Pneumonitis in an Immunocompetent Patient. American Journal of Infectious Diseases and Microbiology. 2020; 8(4):146-148. doi: 10.12691/ajidm-8-4-5


Primary varicella zoster virus (VZV) infection usually affects children and young adults. Symptoms in immunocompetent patients are generally limited to cutaneous manifestations. Pulmonary and neurological manifestations of primary VZV infection are extremely rare and usually described in immunocompromised patients. Acute Disseminated Encephalomyelitis (ADEM), an immune-mediated inflammatory demyelination event often occurring after a viral infection, has been rarely described as occurring after primary VZV infection. We present a case of a previously healthy adult presenting with primary VZV infection complicated by pneumonitis and neurological involvement. To our knowledge, no similar cases were previously described.

varicella zoster virus acute disseminated encephalomyelitis VZV ADEM pneumonitis immunocompetent chickenpox

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