American Journal of Food Science and Technology
ISSN (Print): 2333-4827 ISSN (Online): 2333-4835 Website: http://www.sciepub.com/journal/ajfst Editor-in-chief: Hyo Choi
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American Journal of Food Science and Technology. 2018, 6(6), 258-262
DOI: 10.12691/ajfst-6-6-5
Open AccessArticle

Antioxidant Activity, and α-Glucosidase, α-Amylase and Lipase Inhibitory Activity of Polyphenols in Flesh, Peel, Core and Seed from Mini Apple

Zhaohong Ci1, 2, Kazuto Kikuchi1, Aoi Hatsuzawa1, Arisa Nakai1, Chengyu Jiang1, 2, Atsushi Itadani2, 3 and Michiyuki Kojima2, 3,

1Department of Food Science, Obihiro University of Agriculture and Veterinary Medicine, 11, Nishi-2-sen, Inada-machi, Obihiro, Hokkaido 080-8555, Japan

2United Graduate School of Agricultural Sciences, Iwate University, 3-18-8, Ueda, Morioka, Iwate 020-8550, Japan

3Department of Human Sciences, Obihiro University of Agriculture and Veterinary Medicine, 11, Nishi-2-sen, Inada-machi, Obihiro, Hokkaido 080-8555, Japan

Pub. Date: November 15, 2018

Cite this paper:
Zhaohong Ci, Kazuto Kikuchi, Aoi Hatsuzawa, Arisa Nakai, Chengyu Jiang, Atsushi Itadani and Michiyuki Kojima. Antioxidant Activity, and α-Glucosidase, α-Amylase and Lipase Inhibitory Activity of Polyphenols in Flesh, Peel, Core and Seed from Mini Apple. American Journal of Food Science and Technology. 2018; 6(6):258-262. doi: 10.12691/ajfst-6-6-5

Abstract

Dietary inhibitors of fats and carbohydrates degrading digestive enzymes can reduce obesity and type 2 diabetes. In this study, we investigated and compared polyphenol content, DPPH radical scavenging activity, and inhibitory activity on digestive enzymes, including α-glucosidase, α-amylase and lipase in flesh, peel, core and seed from mini apple (Malu domestica cv. ‘Alps Otome’). Polyphenol content was significantly higher in peel and seed extracts than in flesh and core extracts. As comparing with flesh, peel polyphenols exhibited stronger DPPH radical scavenging activity, and α-amylase and lipase inhibitory activity. Oligomeric polyphenols (Fra.II) were the main polyphenols in seed extracts, which exhibited significantly strong DPPH radical scavenging activity and inhibitory activity on digestive enzymes. However, monomeric polyphenols (Fra.I) were the main polyphenols in core extracts, which exhibited weak inhibitory activity on digestive enzymes than the other parts. Moreover, Fra.III of seed and peel extracts had the highest inhibitory activity on α-glucosidase, followed by Fra.II and Fra.I, respectively. It indicated that more highly polymerized polyphenols from peel and seed of mini apple showed more potent inhibitory activities on α-glucosidase. All of the observations suggested that mini apples possess useful properties. Particularly, it has potential applications for the treatment of diabetes and obesity.

Keywords:
mini apple polyphenol DPPH radical scavenging activity α-glucosidase α-amylase lipase

Creative CommonsThis work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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