American Journal of Food and Nutrition
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American Journal of Food and Nutrition. 2016, 4(4), 93-102
DOI: 10.12691/ajfn-4-4-2
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Ammoniagenesis, Gluconeogenesis and Calcium Exchange in Isolated Kidney Tubules

B.W. Brazier1,

1Bendigo Kangan Institute, Bendigo, Victoria, Australia

Pub. Date: June 07, 2016

Cite this paper:
B.W. Brazier. Ammoniagenesis, Gluconeogenesis and Calcium Exchange in Isolated Kidney Tubules. American Journal of Food and Nutrition. 2016; 4(4):93-102. doi: 10.12691/ajfn-4-4-2


To study the connection between ammoniagenesis, gluconeogenesis and calcium exchange in kidney tubules, isolated kidney tubules were incubated in media with pH 5 and pH 7.2 and the exflux of calcium, ammonia production and cellular ATP levels was measure after a constant time period. Results indicate that calcium transport was reduced in low pH and by ammoniagenesis and increased my acetate and pyruvate and insulin inclusions. Results support the hypothesis that the calcium is controlled by ATP availability and that insulin can affect calcium transport by controlling ATP availability.

ammoniagenesis gluconeogenesis calcium exchange hypercalciuri

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