American Journal of Food and Nutrition
ISSN (Print): 2374-1155 ISSN (Online): 2374-1163 Website: http://www.sciepub.com/journal/ajfn Editor-in-chief: Mihalis Panagiotidis
Open Access
Journal Browser
Go
American Journal of Food and Nutrition. 2020, 8(3), 61-68
DOI: 10.12691/ajfn-8-3-2
Open AccessArticle

Antimicrobial Effect of Non-polar Compounds Extracted from Medicinal Plants

Sana Ghazanfar1, Muhammad Shahid2, , Huadong Liu1 and Muhammad Shafa3

1School of Life Science and Technology, Xian Jiaotong University, West Road, 28#, Xi’an, Shaanxi Province, 710049, P.R. China

2Departmenet of Biochemistry, University of Agriculture Faisalabad, Pakistan

3School of Materials Science and Engineering, Xian Jiaotong University, West Road, 28#, Xi’an, Shaanxi Province, 710049, P.R. China

Pub. Date: September 26, 2020

Cite this paper:
Sana Ghazanfar, Muhammad Shahid, Huadong Liu and Muhammad Shafa. Antimicrobial Effect of Non-polar Compounds Extracted from Medicinal Plants. American Journal of Food and Nutrition. 2020; 8(3):61-68. doi: 10.12691/ajfn-8-3-2

Abstract

The learning is too focussing on identification of compounds dependable for the antimicrobial. Medicinal plants have a significant wellspring of pharmacological impacts that goes about as new of diseases, anti-infections, antioxidant and hostile to malignancy operators. In this study, antimicrobial and antioxidant properties of thyme (Thymus vulgaris L.) black pepper (Piper nigrum L.) Cinnamon (Cinnamomum verum L.) green tea (Camellia sinensis L.) nutmegs (Myristicafragrans Houtt) were investigated. Medicinal plants are generally devoured around the world; green tea contains a lot of non-oxidized flavonoids, named catechins. Therapeutic plants are additionally proof that lessens oxidative pressure hostile to diabetic and switches endothelial brokenness. The examination was led to investigate the antimicrobial and cancer prevention agent properties. The antimicrobial activities were analyzed by disc diffusion test against chosen microbial strain. Anti-microbial activity of n-hexane extract from medicinal plants against two “Gram positive” microscopic organisms viz Staphylococcus aureus and Bacillus subtils two “Gram negative” microorganisms, for example, Pasturellamultocida and Escherichia coli was performed. The antimicrobial effects showed that 30% concentration of n-hexane black pepper (Piper nigrum L.) extract had a strong activity against Bacillus subtills (64±1) and 50% concentration of thyme (Thymus vulgaris L.) extract against Staphylococcus aureus (23±1). The consequences of against oxidant activities uncovered that the most noteworthy all out phenolic substance and complete flavonoid substance were noted after extract of plants. Free radical rummaging action was most extreme in n-hexane extract of plants. Reducing power assay was most extreme extracts of plants. Biofilm activity of plants extracts n-hexane against two bacteria viz Staphylococcus aureus and such as Escherichia coli was done. The extract shows maximum hemolysis of erythrocytes. It was seen that all verified microbial strains were sensitive “>0.82 activity value” to extract that showed a higher antimicrobial impact. Keep in outlook the significance of flavonoids and other bioactive compounds this investigation concentrated on evaluating natural compounds utilizing remove at various fixation.

Keywords:
thyme (Thymus vulgaris L.)) nutmeg (Myristicafragrans Houtt) black pepper (Piper nigrum L.) Cinnamon (Cinnamomum verum L.) green tea (Camellia sinensis L.) n-Hexane

Creative CommonsThis work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

References:

[1]  Monteiro, I.N., et al., Chemical composition and acaricide activity of an essential oil from a rare chemotype of Cinnamomum verum Presl on Rhipicephalus microplus (Acari: Ixodidae). Veterinary parasitology, 2017. 238: p. 54-57.
 
[2]  Ahmed, J., et al., Anti‐fungal bandages containing cinnamon extract. International wound journal, 2019.
 
[3]  Pender, D.N., et al., Effect of water-soluble cinnamon extract on electrocardiographic parameters: An analysis of the CiNNaMON trial. Complementary therapies in medicine, 2018. 41: p. 302-305.
 
[4]  Salehi, B., et al., Thymol, thyme, and other plant sources: Health and potential uses. Phytotherapy Research, 2018. 32(9): p. 1688-1706.
 
[5]  Cutillas, A.-B., et al., Thymus mastichina L. essential oils from Murcia (Spain): Composition and antioxidant, antienzymatic and antimicrobial bioactivities. PloS one, 2018. 13(1): p. e0190790.
 
[6]  Majdi, M., et al., Tissue-specific gene-expression patterns of genes associated with thymol/carvacrol biosynthesis in thyme (Thymus vulgaris L.) and their differential changes upon treatment with abiotic elicitors. Plant physiology and biochemistry, 2017. 115: p. 152-162.
 
[7]  Mosavat, N., et al., Modulation of callus growth and secondary metabolites in different Thymus species and Zataria multiflora micropropagated under ZnO nanoparticles stress. Biotechnology and applied biochemistry, 2019.
 
[8]  Lorenzo-Leal, A.C., E. Palou, and A. Lopez-Malo, Evaluation of the efficiency of allspice, thyme and rosemary essential oils on two foodborne pathogens in in-vitro and on alfalfa seeds, and their effect on sensory characteristics of the sprouts. Int J Food Microbiol, 2019. 295: p. 19-24.
 
[9]  Luo, Y., et al., Characterization of the transcriptional regulator CsbHLH62 that negatively regulates EGCG3" Me biosynthesis in Camellia sinensis. Gene, 2019.
 
[10]  Kheirabadi, Z., et al., Green tea as an adjunctive therapy for treatment of acute uncomplicated cystitis in women: A randomized clinical trial. Complementary therapies in clinical practice, 2019. 34: p. 13-16.
 
[11]  Akroum, S., Antifungal activity of camellia sinensis crude extracts against four species of candida and microsporum persicolor. Journal de mycologie medicale, 2018. 28(3): p. 424-427.
 
[12]  Conger, J.Z. and S. Singg, Effects of Green Tea Consumption on Psychological Health. Therapeutic Advances in Cardiology, 2019. 2: p. 251-255.
 
[13]  Bae, J., et al., Diallyl disulfide potentiates anti-obesity effect of green tea in high-fat/high-sucrose diet-induced obesity. The Journal of nutritional biochemistry, 2019. 64: p. 152-161.
 
[14]  Zuo, H.-j., et al., In vitro and in vivo evaluation of antitumor activity of Ligustrum robustum, a Chinese herbal tea. Chinese journal of integrative medicine, 2018: p. 1-6.
 
[15]  Carlsen, M.H., R. Blomhoff, and L.F. Andersen, Intakes of culinary herbs and spices from a food frequency questionnaire evaluated against 28-days estimated records. Nutrition journal, 2011. 10(1): p. 50.
 
[16]  Silvis, I., et al., Similarities and differences of the volatile profiles of six spices explored by Proton Transfer Reaction Mass Spectrometry. Food chemistry, 2019. 271: p. 318-327.
 
[17]  Macwan, S.R., et al., Essential oils of herbs and spices: Their antimicrobial activity and application in preservation of food. International Journal of Current Microbiology and Applied Sciences, 2016. 5(5): p. 885-901.
 
[18]  Myszka, K., K. Leja, and M. Majcher, A current opinion on the antimicrobial importance of popular pepper essential oil and its application in food industry. Journal of Essential Oil Research, 2019. 31(1): p. 1-18.
 
[19]  Kanakabandi, C. and T. Goswami, Determination of properties of black pepper to use in discrete element modeling. Journal of Food Engineering, 2019. 246: p. 111-118.
 
[20]  Archana, S. and J. Abraham, Comparative analysis of antimicrobial activity of leaf extracts from fresh green tea, commercial green tea and black tea on pathogens. Journal of Applied Pharmaceutical Science, 2011. 1(8): p. 149.
 
[21]  Kousar, N., et al., Synthesis, characterization and antimicrobial activities of organotin (IV) complexes with ethylthioglycolate. Chemistry International, 2015. 1(2): p. 92-98.
 
[22]  Dewanto, V., et al., Thermal processing enhances the nutritional value of tomatoes by increasing total antioxidant activity. Journal of agricultural and food chemistry, 2002. 50(10): p. 3010-3014.
 
[23]  Zia udDen, N. and M. Shahid, Determination of Bioactive Properties of Different Temperature Camellia sinensis (Green Tea). American Journal of Food and Nutrition, 2017. 5(1): p. 10-18.
 
[24]  Banerjee, S., et al., Antioxidant and antimicrobial activity of Araucaria cookii and Brassaia actinophyla. Pakistan Journal of Biological Sciences, 2014. 17(5): p. 715-719.
 
[25]  Tejs, S., The Ames test: a methodological short review. Environmental Biotechnology, 2008. 4: p. 7-14.
 
[26]  Kim, J.-a., et al., Epigallocatechin gallate, a green tea polyphenol, mediates NO-dependent vasodilation using signaling pathways in vascular endothelium requiring reactive oxygen species and Fyn. Journal of Biological Chemistry, 2007. 282(18): p. 13736-13745.
 
[27]  Masurkar, S.A., et al., Rapid biosynthesis of silver nanoparticles using Cymbopogan citratus (lemongrass) and its antimicrobial activity. Nano-micro letters, 2011. 3(3): p. 189-194.
 
[28]  Dehpour, A.A., et al., Antioxidant activity of the methanol extract of Ferula assafoetida and its essential oil composition. Grasas y aceites, 2009. 60(4): p. 405-412.
 
[29]  Djeridane, A., et al., Antioxidant activity of some Algerian medicinal plants extracts containing phenolic compounds. Food chemistry, 2006. 97(4): p. 654-660.
 
[30]  Singh, G., et al., Chemical constituents, antifungal and antioxidative potential of Foeniculum vulgare volatile oil and its acetone extract. Food control, 2006. 17(9): p. 745-752.
 
[31]  Leta, G.C., P.A. Mourão, and A.M. Tovar, Human venous and arterial glycosaminoglycans have similar affinity for plasma low-density lipoproteins. Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease, 2002. 1586(3): p. 243-253.