American Journal of Food and Nutrition
ISSN (Print): 2374-1155 ISSN (Online): 2374-1163 Website: http://www.sciepub.com/journal/ajfn Editor-in-chief: Mihalis Panagiotidis
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American Journal of Food and Nutrition. 2019, 7(4), 158-165
DOI: 10.12691/ajfn-7-4-6
Open AccessArticle

Development of Low Glycemic Index Rice and Its Effectiveness in the Regulation of Postprandial Glucose Response in Type 2 Diabetes

Prasanthi Prabhakaran Sobhana1, Jeyakumar Shanmugam Murugaiha2, Panda Hrusikesh3, Srinivas Epparapalli1 and Damayanti Korrapati1,

1Department of Dietetics, National Institute of Nutrition, Jamai Osmania P.O., Hyderabad-500007

2Lipid chemistry, National Institute of Nutrition, Jamai Osmania P.O., Hyderabad-500007

3Media, Communications and Extension Group, National Institute of Nutrition, Jamai Osmania P.O., Hyderabad-500007

Pub. Date: December 22, 2019

Cite this paper:
Prasanthi Prabhakaran Sobhana, Jeyakumar Shanmugam Murugaiha, Panda Hrusikesh, Srinivas Epparapalli and Damayanti Korrapati. Development of Low Glycemic Index Rice and Its Effectiveness in the Regulation of Postprandial Glucose Response in Type 2 Diabetes. American Journal of Food and Nutrition. 2019; 7(4):158-165. doi: 10.12691/ajfn-7-4-6

Abstract

Background/Objective: To determine the glycemic index (GI) of RNR15048 rice variety and study its effectiveness in reducing postprandial blood glucose levels and the regulation of lipid profile in patients with type 2 diabetes. Subjects/Methods: The GI of RNR15048 rice was measured in 54 healthy subjects in the age group of 30-50 years. The dietary intervention study was conducted in 80 subjects with diabetes in the age group of 40-60 years where 40 test subjects replaced their regular rice with RNR 15048 rice variety for 3 months. Anthropometric and biochemical parameters, HbA1c, fasting blood glucose, lipid profile, insulin were determined before and after the study. Results: The glycemic index (GI) of RNR 15048 rice variety was observed to be low with GI of 51.72 ± 3.39. The dietary intervention study in type 2 diabetic subjects revealed significant decrease in fasting blood glucose (158.4 ± 9.30 vs 140.2 ± 8.87 mg/dL) and HbA1c levels (7.1 ± 0.34 vs 6.1 ± 0.33 %) with an increase in HDL levels (33.7 ± 1.29 vs 37.1 ± 1.83 mg/dL) while parameters such as body weight, blood pressure and insulin levels did not show any significant changes. Conclusion: Low GI rice is effective in the reduction of postprandial glucose response in type 2 diabetes and increase in plasma HDL levels and therefore useful in the management of type 2 diabetes and in the long term management of cardiovascular diseases.

Keywords:
blood glucose glycemic index glycosylated haemoglobin low GI rice

Creative CommonsThis work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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