American Journal of Food and Nutrition
ISSN (Print): 2374-1155 ISSN (Online): 2374-1163 Website: http://www.sciepub.com/journal/ajfn Editor-in-chief: Mihalis Panagiotidis
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American Journal of Food and Nutrition. 2019, 7(3), 107-112
DOI: 10.12691/ajfn-7-3-5
Open AccessArticle

A Single Arm Trial in Treatment of CKD Patients with Sodium Copper Chlorophyllin Formulation

Suresh Patankar1, Atul Sajgure1, Chitra Savangikar2, , Vasant Savangikar2, Sharvari Rangnekar3 and Milind Gharpure4

1ACE Multispecialty Hospital, S No- 32/2A, Erandwana, GulawaniMaharaj Road, Near Mehandale Garage, Opp. Hotel Abhishek, Pune, Maharashtra 411004 India

2PhytabolitesNeutraceuticals Pvt. Ltd. 4, Tapasvi Apt. Prasanna colony, Indiranagar, Nashik 422009 India

3Quest Clinical Services, 14, Samata, Ganeshnagar, Chinchwad, Pune, Maharashtra-411033 India

4Thinq Pharma –CRO Pvt. Ltd., Road no. 9, Wagle estate MIDC, Thane, Mumbai400604 India

Pub. Date: October 28, 2019

Cite this paper:
Suresh Patankar, Atul Sajgure, Chitra Savangikar, Vasant Savangikar, Sharvari Rangnekar and Milind Gharpure. A Single Arm Trial in Treatment of CKD Patients with Sodium Copper Chlorophyllin Formulation. American Journal of Food and Nutrition. 2019; 7(3):107-112. doi: 10.12691/ajfn-7-3-5

Abstract

In a prospective, single arm study of 34 Chronic Kidney Disease (CKD) patients in a trial of 90 days wherein patients got standard-of-care treatment and liquid composition containing Sodium Copper Chlorophyllin, the Investigational Product (IP), as add-on treatment for first 60 days and patients were ‘off’ the IP for last 30 days. Significant reduction in serum creatinine, Blood Urea and Uric acid level and significant improvement in estimated Glomerular Filtration Rate (eGFR), and Health related criteria for quality of life were observed in 60 days’ period of administration. eGFR remained significantly higher on 90th day than 0 day despite withdrawal of IP after 60 days. These observations suggest partial/limited reversal of lost kidney function as a lingering effect of the IP. Both these are first observations opening up new avenues for improving life of CKD patients. This is first clinical trial report of an orally consumed product that decreases serum creatinine and also actually improved health related quality of life within 60 days and a surprising evidence that suggests significant degree of restoration of kidney function in the progressively degenerative disease CKD. This clinical trial opens opportunities for managing CKD that were never available so far.

Keywords:
chronic kidney disease copper chlorophyllin creatinine blood urea quality of life

Creative CommonsThis work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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