American Journal of Epidemiology and Infectious Disease
ISSN (Print): 2333-116X ISSN (Online): 2333-1275 Website: http://www.sciepub.com/journal/ajeid Editor-in-chief: Apply for this position
Open Access
Journal Browser
Go
American Journal of Epidemiology and Infectious Disease. 2017, 5(1), 8-13
DOI: 10.12691/ajeid-5-1-2
Open AccessArticle

Seasonal Distribution of Dengue Fever in the Central Highlands Region, Vietnam (2010- 2015)

Le Van Tuan1, , Nguyen Thi Tuyet Van1, Phan Thi Tuyet Nga1, Le Duong Minh Quan1 and Pham Tho Duoc2

1Department of Virology, Tay Nguyen Institute of Hygiene and Epidemiology, 34 Pham Hung Street, Buon Ma Thuot city, DakLak, Vietnam

2Department of Epidemiology, Tay Nguyen Institute of Hygiene and Epidemiology, DakLak, Vietnam

Pub. Date: March 03, 2017

Cite this paper:
Le Van Tuan, Nguyen Thi Tuyet Van, Phan Thi Tuyet Nga, Le Duong Minh Quan and Pham Tho Duoc. Seasonal Distribution of Dengue Fever in the Central Highlands Region, Vietnam (2010- 2015). American Journal of Epidemiology and Infectious Disease. 2017; 5(1):8-13. doi: 10.12691/ajeid-5-1-2

Abstract

Background: Dengue virus infection has emerged as a notable public health problem in recent decades in terms of the mortality and morbidity associated with it. Dengue has been known to be endemic in the Central Highlands region, Vietnam for over 30 years. Here we have reported the trend of Dengue fever cases in the Central Highlands region, Vietnam for a period of 2010- 2015. Methods: Serum samples from clinically suspected cases of dengue virus infection were collected. All samples were tested for Dengue IgM by indirect ELISA and by RT-PCR for presence of Dengue virus RNA. Results: A total of 3272 serum samples were tested, of which 1229 (37.5%) were positive for dengue. The Dengue positive patients were 565 males and 664 females. All four serotypes of Dengue virus have found in the Central Highlands region. DENV-2 was predominant in 2010, 2012 and 2013. DENV-3 and DENV-4 was predominant in 2014 and 2015; respectively. The Dengue affected cases were more in 20-40 years age group. Dengue cases were more during May to September in rainy season when weather conditions were prefer for mosquito bleeding and vector activity. Conclusions: The findings of this study indicate that all four serotypes of dengue virus are circulating in the Central Highlands region, Vietnam. The data enable to notice seasonal distribution of Dengue fever in the Central Highlands region, Vietnam over five years (2010-2015) with regards to outbreaks and peak incidences in the disease.

Keywords:
dengue virus serotype the central highlands vietnam

Creative CommonsThis work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

References:

[1]  Henchal EA, Putnak JR: The dengue viruses. Clin Microbiol Rev 1990, 3(4):376-396.
 
[2]  WHO: Dengue: a global threat – global answers. Global strategy for dengue prevention and control 2012-2020 2012:43.
 
[3]  Vuong HA, Huong VT, Phuong NA: Hemorrhagic Dengue fever in the Central Highlands in 1992. Journal of Tay Nguyen preventive medicine 1992: 27-31.
 
[4]  Vuong HA, Phuong NA, Huong LTV: Some epidemiological characteristics of Dengue Hemorrhagic fever in the three provinces of the Central Highlands during 1983 to 1992. Journal of Tay Nguyen preventive medicine 1993:38-45.
 
[5]  Vuong HA, Phuong NA, Huong LTV: Some epidemiological characteristics of Dengue Hemorrhagic fever in Dak Lak 1893-1990. Journal of Tay Nguyen preventive medicine 1995: 20-28.
 
[6]  Dat DT, Huong VT: Epidemiologic characteristics of Dengue fever in the Central Highlands of Vietnam, 1998-2010. Journal of Tay Nguyen Medicine Prevention 2010, 2:1-3.
 
[7]  Duoc PT, Dat DT, Trang LTT, Van NTH: Epidemiologic characteristics of Dengue fever in the Central Highlands of Vietnam, 2008-2012. Journal of Tay Nguyen Preventive Medicine 2014, 1: 41-47.
 
[8]  Lanciotti RS, Calisher CH, Gubler DJ, Chang GJ, Vorndam AV: Rapid detection and typing of dengue viruses from clinical samples by using reverse transcriptase-polymerase chain reaction. J Clin Microbiol 1992, 30(3):545-551.
 
[9]  Murray NE, Quam MB, Wilder-Smith A: Epidemiology of dengue: past, present and future prospects. Clinical Epidemiology 2013, 5: 299-309.
 
[10]  Halstead SB: More dengue, more questions. Emerging infectious diseases 2005, 11(5):740-741.
 
[11]  Halstead SB, Scanlon JE, Umpaivit P, Udomsakdi S: Dengue and chikungunya virus infection in man in Thailand, 1962-1964. IV. Epidemiologic studies in the Bangkok metropolitan area. The American journal of tropical medicine and hygiene 1969, 18(6): 997-1021.
 
[12]  Huy R, Buchy P, Conan A, Ngan C, Ong S, Ali R, Duong V, Yit S, Ung S, Te V et al: National dengue surveillance in Cambodia 1980-2008: epidemiological and virological trends and the impact of vector control. Bulletin of the World Health Organization 2010, 88(9): 650-657.
 
[13]  Kongsomboon K, Singhasivanon P, Kaewkungwal J, Nimmannitya S, Mammen MP, Jr., Nisalak A, Sawanpanyalert P: Temporal trends of dengue fever/dengue hemorrhagic fever in Bangkok, Thailand from 1981 to 2000: an age-period-cohort analysis. The Southeast Asian journal of tropical medicine and public health 2004, 35(4): 913-917.
 
[14]  Thai KT, Nagelkerke N, Phuong HL, Nga TT, Giao PT, Hung LQ, Binh TQ, Nam NV, De Vries PJ: Geographical heterogeneity of dengue transmission in two villages in southern Vietnam. Epidemiology and infection 2010, 138(4): 585-591.
 
[15]  Luo L, Liang HY, Hu YS, Liu WJ, Wang YL, Jing QL, Zheng XL, Yang ZC: Epidemiological, virological, and entomological characteristics of dengue from 1978 to 2009 in Guangzhou, China. Journal of vector ecology: journal of the Society for Vector Ecology 2012, 37(1):230-240.
 
[16]  Vuong HA, Huong VT: Dengue fever/Hemorrhagic dengue fever outbreak in the Central Highlands, 1998. Journal of Tay Nguyen preventive medicine 2000, 15: 31-39.
 
[17]  Huong VT, Vuong HA, Chi NTC: Epidemiological characteristics of dengue hemorrhagic fever in the Central Highlands, 1998-2004. Journal of Tay Nguyen preventive medicine 2005, 2:12-16.
 
[18]  Guzman MG, Kouri GP, Bravo J, Soler M, Vazquez S, Morier L: Dengue hemorrhagic fever in Cuba, 1981: a retrospective seroepidemiologic study. The American journal of tropical medicine and hygiene 1990, 42(2): 179-184.
 
[19]  Ooi EE, Goh KT, Gubler DJ: Dengue prevention and 35 years of vector control in Singapore. Emerging infectious diseases 2006, 12(6):887-893.
 
[20]  Rigau-Perez JG, Vorndam AV, Clark GG: The dengue and dengue hemorrhagic fever epidemic in Puerto Rico, 1994-1995. The American journal of tropical medicine and hygiene 2001, 64 (1-2): 67-74.
 
[21]  Teng A, Singh S: Epidemiology and new initiatives in the prevention and control of dengue in Malaysia. Dengue Bull 2001, 25: 7-12.
 
[22]  Balmaseda A, Hammond SN, Tellez Y, Imhoff L, Rodriguez Y, Saborio SI, Mercado JC, Perez L, Videa E, Almanza E et al: High seroprevalence of antibodies against dengue virus in a prospective study of schoolchildren in Managua, Nicaragua. Tropical medicine & international health: TM & IH 2006, 11(6): 935-942.
 
[23]  San Martin JL, Brathwaite O, Zambrano B, Solorzano JO, Bouckenooghe A, Dayan GH, Guzman MG: The epidemiology of dengue in the americas over the last three decades: a worrisome reality. The American journal of tropical medicine and hygiene 2010, 82(1): 128-135.
 
[24]  Teixeira MG, Costa MC, Coelho G, Barreto ML: Recent shift in age pattern of dengue hemorrhagic fever, Brazil. Emerging infectious diseases 2008, 14(10): 1663.
 
[25]  Khun S, Manderson L: Community and school-based health education for dengue control in rural Cambodia: a process evaluation. PLoS neglected tropical diseases 2007, 1(3): e143.
 
[26]  Chitnis N, Schapira A, Smith T, Steketee R: Comparing the effectiveness of malaria vector-control interventions through a mathematical model. The American journal of tropical medicine and hygiene 2010, 83(2): 230-240.
 
[27]  Wichmann O, Hongsiriwon S, Bowonwatanuwong C, Chotivanich K, Sukthana Y, Pukrittayakamee S: Risk factors and clinical features associated with severe dengue infection in adults and children during the 2001 epidemic in Chonburi, Thailand. Tropical medicine & international health: TM & IH 2004, 9(9): 1022-1029.
 
[28]  Guha-Sapir D, Schimmer B: Dengue fever: new paradigms for a changing epidemiology. Emerging themes in epidemiology 2005, 2(1):1.
 
[29]  Limkittikul K, Brett J, L'Azou M: Epidemiological trends of dengue disease in Thailand (2000-2011): a systematic literature review. PLoS neglected tropical diseases 2014, 8(11):e3241.
 
[30]  Mia MS, Begum RA, Er AC, Abidin RD, Pereira JJ: Trends of dengue infections in Malaysia, 2000-2010. Asian Pacific journal of tropical medicine 2013, 6(6):462-466.