American Journal of Cancer Prevention
ISSN (Print): 2328-7314 ISSN (Online): 2328-7322 Website: Editor-in-chief: Nabil Abdel-Hamid
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American Journal of Cancer Prevention. 2018, 6(1), 1-4
DOI: 10.12691/ajcp-6-1-1
Open AccessArticle

Carcinoma of Unknown Primary: A Case Report

Roslin Jose1, Prerana Suresh Kurtkoti1, Kavyamala1, Sai Subramanyam K1, Sunit Lokwani2, Jayashankar CA1, , Dyna Jones1, Rohith N1, Venkata Bharat Kumar Pinnelli3 and Venkata Ramana Kandi4

1Department of General Medicine, Vydehi Institute of Medical Sciences and Research Centre, #82, EPIP Area, Nallurhalli, Whitefield, Bangalore – 560066, Karnataka

2Department of Medical Oncology, Vydehi Institute of Medical Sciences and Research Centre, #82, EPIP Area, Nallurhalli, Whitefield, Bangalore – 560066, Karnataka

3Department of Biochemistry, Vydehi Institute of Medical Sciences and Research Centre, #82, EPIP Area, Nallurhalli, Whitefield, Bangalore – 560066, Karnataka

4Department of Microbiology, Prathima Institute of Medical Sciences, Karimnagar, Telangana, India

Pub. Date: February 02, 2018

Cite this paper:
Roslin Jose, Prerana Suresh Kurtkoti, Kavyamala, Sai Subramanyam K, Sunit Lokwani, Jayashankar CA, Dyna Jones, Rohith N, Venkata Bharat Kumar Pinnelli and Venkata Ramana Kandi. Carcinoma of Unknown Primary: A Case Report. American Journal of Cancer Prevention. 2018; 6(1):1-4. doi: 10.12691/ajcp-6-1-1


Cancer of unknown primary (CUP), is a rare malignancy with unknown site of origin. The disease accounting for 2%-3% of all fatal malignancies, have variable histologic tumour types and clinical presentations. The present study discusses a case of CUP in a 68-year-old male subject, presenting with a 6-month history of abdominal pain in the upper abdomen. The patient was a chronic smoker and had the presence of bilateral testicular swelling for the past 15 years. The clinical examination of the patient revealed bilateral inguinal lymphadenopathy. The findings of the abdominal CT scan and the bone biopsy of the patient suggested metastatic carcinoma. 18F-fluorodeoxyglucose PET CT scan showed lytic lesions. The study recommends the need for a focused search, comprising of robust immunohistochemical profiling, for locating the primary tumors in CUP.

cancer of unknown primary (CUP) tumor malignancies metastatic carcinoma biopsy immunohistochemical profiling

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