American Journal of Cancer Prevention
ISSN (Print): 2328-7314 ISSN (Online): 2328-7322 Website: http://www.sciepub.com/journal/ajcp Editor-in-chief: Nabil Abdel-Hamid
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American Journal of Cancer Prevention. 2017, 5(1), 17-20
DOI: 10.12691/ajcp-5-1-3
Open AccessCase Report

Extranuchal-type Fibroma Mimicking Low Grade Sarcoma: A Case Report and Review of the Literature

Mazaher Ramezani1, Marziyeh Masnadjam1 and Masoud Sadeghi2,

1Molecular Pathology Research Center, Emam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran

2Medical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran

Pub. Date: March 14, 2017

Cite this paper:
Mazaher Ramezani, Marziyeh Masnadjam and Masoud Sadeghi. Extranuchal-type Fibroma Mimicking Low Grade Sarcoma: A Case Report and Review of the Literature. American Journal of Cancer Prevention. 2017; 5(1):17-20. doi: 10.12691/ajcp-5-1-3

Abstract

Nuchal-type fibroma (NTF) is a rare fibrous growth that developing in the nuchal region, in some instances it occurs at the extranuchal sites. Herein, this study reported a case of NTF on extranuchal site in an Iranian girl in Western Iran. The report included a 14-year-old girl with a chief complaint of right hemithorax suprascapular soft tissue mass since 6 years ago and tenderness since last month that physical examination showed firm, tender, non-erythematous mass measuring 5x10 cm with adhesion to surrounding tissue was noted on the right hemithorax over the scapula. Frozen section diagnosis showed spindle cell tumor compatible with low grade sarcoma, but the pathologist reported an extranuchal-type fibroma in permanent. In conclusion, NTF occurs more frequently in middle-aged adults and is more common in men. The prevalence of nuchal region is more than extranuchal region in NTF patients. The NTF is associated with trauma more than Gardner’s syndrome. Also, the pathologist and surgeon must be aware of this entity, especially at extranuchal sites, not to be misinterpreted as sarcoma.

Keywords:
extranuchal-type fibroma low grade sarcoma case report

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References:

[1]  Diwan AH, Graves ED, King JA, Horenstein MG. Nuchal-type fibroma in two related patients with Gardner's syndrome. Am J Surg Pathol. 2000; 24(11): 1563-7.
 
[2]  Enzinger FM, Weiss SW. Benign Tumors and Tumorlike Lesions of the Fibrous Tissue, 2nd C.V. Mosby, St. Louis, MO. 1988: 102-35.
 
[3]  Lee GK, Suh KJ, Lee SM, Lee SJ. Nuchal-type fibroma of the buttock: magnetic resonance imaging findings. Jpn J Radiol. 2010; 28(7): 538-41.
 
[4]  Kim DH, Kim TH, Sung NH, Shin H, Lee AY, Lee SH. Multiple nuchal-type fibromas on the scalp: a case report. Ann Dermatol. 2015; 27(2): 194-6.
 
[5]  Gong Y, Zhao X, Wu DI, Liu J. Nuchal-type fibroma of the shoulder: A case report and review of the literature. Oncol Lett. 2016; 11(6): 4152-4.
 
[6]  Abe M, Nagai Y, Okada E, Aoyama K, Tamura A, Ishikawa O. Case of nuchal fibroma. J Dermatol. 2007; 34(7): 498-500.
 
[7]  Linos K, Sedivcová M, Cerna K, Sima R, Kazakov DV, Nazeer T, et al. Extra nuchal-type fibroma associated with elastosis, traumatic neuroma, a rare APC gene missense mutation, and a very rare MUTYH gene polymorphism: a case report and review of the literature. J Cutan Pathol. 2011; 38(11): 911-8.
 
[8]  Michal M, Fetsch JF, Hes O, Miettinen M. Nuchal-type fibroma: a clinicopathologic study of 52 cases. Cancer. 1999;85(1):156-63.
 
[9]  Shin JB, Son SW, Kim IH. Nuchal-type fibroma of the coccyx. Ann Dermatol.2008; 20(1): 41-4.
 
[10]  Sraj SA, Lahoud LE, Musharafieh R, Taha A. Nuchal-type fibroma of the ankle: a case report. J Foot Ankle Surg. 2008; 47(4): 332-6.
 
[11]  Karonidis A, Rigby HS, Orlando A. Collagenosis nuchae: a case report of a rare and often misdiagnosed condition. J Plast Reconstr Aesthet Surg. 2007; 60(3): 320-3.
 
[12]  Banney L, Weedon D, Muir J. Nuchal fibroma associated with scleredema, diabetes mellitus and organic solvent exposure. Australas J Dermatol. 2000; 41(1): 39-41.
 
[13]  Diwan AH, Horenstein MG. Dermatofibrosarcoma protuberans association with nuchal-type fibroma. J Cutan Pathol. 2004; 31(1): 62-6.
 
[14]  Tsunemi Y, Saeki H, Tamaki K. Nuchal fibroma clearly visualized by computed tomography: a case report. Int J Dermatol. 2005; 44(8): 703-4.
 
[15]  Alsaleh N, Amanguno H. Nuchal Fibroma : A rare entity of neck masses. Gulf J Oncolog. 2015; 1(18): 10-2.
 
[16]  Hameed M, Benevenia J, Blacksin M, Aisner SC. Nuchal fibroma of the shoulder involving skeletal muscle: a radiographic and clinicopathological study. A case report. J Bone Joint Surg Am. 1998; 80(11): 1684-6.
 
[17]  Lee SE, Kim YC, Kim SC. Nuchal fibroma presenting as two posterior neck masses. J Dermatol. 2007; 34(4): 262-3.
 
[18]  Yokoyama S, Nakano H, Kaneko T, Hanada K. A Japanese case of nuchal-type fibroma. J Dermatol. 2005; 32(11): 931-2.
 
[19]  Lee CC, Lai CS, Lin CH, Lin YN, Chu SC, Chai CY, et al. Extra nuchal-type fibroma associated with repetitive blunt trauma during religious activities. Trauma Case Reports.2016; 4: 16-20.
 
[20]  Balachandran K, Allen PW, MacCormac LB. Nuchal fibroma. A clinicopathological study of nine cases. Am J Surg Pathol. 1995; 19(3): 313-7.