American Journal of Cancer Prevention
ISSN (Print): 2328-7314 ISSN (Online): 2328-7322 Website: http://www.sciepub.com/journal/ajcp Editor-in-chief: Nabil Abdel-Hamid
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American Journal of Cancer Prevention. 2015, 3(5), 89-90
DOI: 10.12691/ajcp-3-5-3
Open AccessResearch Article

Rectal Cancer in Patient with Chronic Lymphocytic Leukemia Association with Brucellosis: The First Case Report

Mehrdad Payandeh1, Edris Sadeghi2, 3, , Masoud Sadeghi2, 3 and Fariba Falsafi4

1Department of Hematology and Medical Oncology, Kermanshah University of Medical Sciences, Kermanshah, Iran

2Student Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran

3Medical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran

4Department of Nursing, Borujerd Branch, Islamic Azad University, Borujerd, Iran

Pub. Date: October 07, 2015
(This article belongs to the Special Issue Advances in Non-Hodgkin Lymphomas)

Cite this paper:
Mehrdad Payandeh, Edris Sadeghi, Masoud Sadeghi and Fariba Falsafi. Rectal Cancer in Patient with Chronic Lymphocytic Leukemia Association with Brucellosis: The First Case Report. American Journal of Cancer Prevention. 2015; 3(5):89-90. doi: 10.12691/ajcp-3-5-3

Abstract

Introduction: Colorectal cancer is the fourth most common cancer in men and the third most common in women. Brucella infections in immune compromised hosts (like CLL) are relatively rare. Herein, we reported first case report, a patient have been diagnosed as simultaneous CLL and brucellosis during his follow up that she indicated a subsequent neoplasm after CLL according to our knowledge. Case Report: A 77-year-old male, presented to his primary care provider with complaint of weakness and fatigue. After analysis with bone marrow aspiration and biopsy, there was heavy infiltration with well-differentiated small lymphocytes so we diagnosed CLL for her problems. Then he was treated with prednisolone and cyclophosphamide with allopurinol. During the treatment period (about one year after the first visit), the patient was suffering from brucellosis that treated with cotrimoxazole + rifampicin regimen. In the continued his treatment, he had been treated with danazol and then intravenous immunoglobulin for a few attack of severe pneumonia. Recently he suffer of complaint of hematochezia, then refer for rectosigmoidoscopy with rectal mass lesion. In pathology reported well differentiation rectum adenocarcinoma. He had chemo irradiation with capecitabine and then with adjuvant regimen of CAPOX (Xeloda with oxaliplatin). At now he is alive with classic follow up. Conclusion: In patients with CLL and brucellosis we suggest that treatment for infection and leukemia simultaneously and we have enough notice about the patient's conditions because it may be created second non hematological malignancy. These clinical procedures make life more for the patient.

Keywords:
Brucellosis CLL Hematochezia Rectal cancer

Creative CommonsThis work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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