American Journal of Cancer Prevention
ISSN (Print): 2328-7314 ISSN (Online): 2328-7322 Website: http://www.sciepub.com/journal/ajcp Editor-in-chief: Nabil Abdel-Hamid
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American Journal of Cancer Prevention. 2015, 3(3), 65-67
DOI: 10.12691/ajcp-3-3-5
Open AccessResearch Article

Association between of BMI and Blood Groups with Breast Cancer Incidence among Women of West Iran: A Case-control Study

Mehrdad Payandeh1, Babak Shazad1, Masoud Sadeghi2, 3, , Nahid Bahari2, 3 and Edris Sadeghi2, 3

1Department of Hematology and Medical Oncology, Kermanshah University of Medical Sciences, Kermanshah, Iran

2Students Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran

3Medical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran

Pub. Date: May 31, 2015
(This article belongs to the Special Issue Advances in Breast Cancer)

Cite this paper:
Mehrdad Payandeh, Babak Shazad, Masoud Sadeghi, Nahid Bahari and Edris Sadeghi. Association between of BMI and Blood Groups with Breast Cancer Incidence among Women of West Iran: A Case-control Study. American Journal of Cancer Prevention. 2015; 3(3):65-67. doi: 10.12691/ajcp-3-3-5

Abstract

Background: Breast cancer accounts about one fifth of all female malignancy. This cancer is the leading cause of death in high income countries and second leading cause in low and middle income countries. The aim of study is to evaluate a number of factors in the patients of breast cancer compared to controls in West Iran and correlation of them with breast cancer incidence. Patients and Methods: In 2014, 76 patients with breast cancer and invasive ductal carcinoma (cases) and 81 age and sex matched-controls randomly were interred to our study. We compared blood groups, BMI, age at the first menarche and hypertension in both groups. Results: In case group, the frequency of A+, O+, B+ and AB+ was 40.8%, 28.9%, 14.5% and 9.2%, respectively. Also, the frequency of A-, B-, AB-, O- with each other was 6.5%. In control group, A+, O+, B+ and AB+ was 27.2%, 34.6%, 21% and 8.6%, respectively. The frequency of BMI in two groups was almost similar. Of 76 patients, 13.2% had hypertension and also of 81 controls, 16% had hypertension. The mean age t the first menarche for cases was 13.75 years and for controls was 13.77 years. There was significant correlation between of these variables with breast cancer incidence (P>0.05). Conclusions: Blood groups, BMI, age at the first menarche and hypertension are not singly risk factors for breast cancer incidence, but probably combination of them can increases breast cancer incidence. In our opinion, the link between of breast cancer and listed variables is unexplained.

Keywords:
blood group BMI breast cancer case-control study

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