American Journal of Cancer Prevention
ISSN (Print): 2328-7314 ISSN (Online): 2328-7322 Website: Editor-in-chief: Nabil Abdel-Hamid
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American Journal of Cancer Prevention. 2015, 3(2), 35-44
DOI: 10.12691/ajcp-3-2-3
Open AccessArticle

Quality of Life of Patients Undergoing Cancer Treatment in B.P. Koirala Memorial Cancer Hospital, Bharatpur, Chitwan, Nepal

Radha Acharya Pandey1, , Govinda Prasad Dhungana2, Jyotsana Twi Twi1, Sudeepa Byanju1 and Barsha Khawas1

1Nursing Department, Kathmandu University School of Medical Sciences, Dhulikhel Hospital Kathmandu University Hospital, Dhulikhel, Nepal

2Chitwan Medical College, Bharatpur, Chitwan, Nepal

Pub. Date: April 15, 2015

Cite this paper:
Radha Acharya Pandey, Govinda Prasad Dhungana, Jyotsana Twi Twi, Sudeepa Byanju and Barsha Khawas. Quality of Life of Patients Undergoing Cancer Treatment in B.P. Koirala Memorial Cancer Hospital, Bharatpur, Chitwan, Nepal. American Journal of Cancer Prevention. 2015; 3(2):35-44. doi: 10.12691/ajcp-3-2-3


This research entitled “Quality of Life of Patients Undergoing Cancer Treatment in B.P. Koirala Memorial Cancer Hospital, Bharatpur, Chitwan” was conducted to assess the quality of life of cancer patients. It was carried out among patients attending B. P. Koirala Memorial Cancer Hospital, Bharatpur, Chitwan. Background: In patients with different type of cancers and the quality of life (QoL) improvement is the main goal, since survival can be prolonged marginally. A diagnosis is very stressful for people, affecting all aspects of their being and quality of life. Up to date, knowledge on QoL impairments throughout the entire treatment process, often including several treatment modalities is scarce. One objective of this study was to assess the quality of life of cancer patient undergoing cancer treatment. Methods: A quantitative, cross-sectional, descriptive, design was adapted. A total of 245 cancer patients above 20 years old, were enrolled in the studies during August-September, 2013. Inclusion criteria were patients who had already received at least one type of cancer treatment and had attended the hospital for receiving the same or next type of treatment again. Exclusion criteria were any other chronic co-morbidity condition that could be influenced their QoL. The most commonly listed medical co-morbidities were: diabetes mellitus, hypertension, coronary artery disease. Cancer patients who have Eastern Co-operative Oncology Group (ECOG) performance status of 4 (i.e. fully bed-ridden) were excluded from the study. The data was collected by interview, using modified, structured scale of European Organization for Research and Treatment of Cancer Quality of life Questionnaire (EORTC QLQ- C30), prepared by the EORTC group. Information about the patient’s disease condition and treatment were obtained from the patient’s medical records. The collected data was analyzed by using SPSS version 16. Descriptive and inferential statistics were used to describe the respondent’s quality of life (QoL) scores and to identify the factors affecting it respectively. Results: The study findings revealed the quality of life of cancer patients to be influenced by many factors such as: site of cancer, stage of cancer, time elapsed since diagnosis and Eastern Co-operative Oncology Group (ECOG) performance status. The average QoL scores (out of 100) for different scales were 85.54 (global health/QoL), 77.03 (functional), and 16.14 (symptom). Loss of appetite was the most frequent complaint (mean = 20.27) and was present in almost all the patients. As the overall QoL of the patients was significantly correlated with different QoL scales as-, cognitive, emotional, physical, social, role functioning, pain, fatigue, dyspnoea, loss of appetite and nausea/vomiting and financial problem. Conclusion: Hence, in average, the quality of life of cancer patients was found to be relatively better, although there were higher ratings for some (as: cognitive, physical, role and emotional functioning) and lower for others (like social functioning). Additional research should be done in this area for improving the quality of life of specific type of cancer patients in Nepal, though the findings of this study are expected to provide the baseline knowledge regarding it.

quality of life cancer patient EORTC QLQ- C30

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[1]  Global Health Observatory (GHO, 2012). Cancer mortality and morbidity. Available at (retrieved on 26th june, 2013).
[2]  American Cancer Society (2013). Cancer Facts & Figures 2013. Annual report (2013). Available at (Retrieved on 2nd July, 2013).
[3]  World Health Organization, (2006). Focus in Priorities, WHO Report 2005, Available at (Retrieved on 26th June, 2013).
[4]  Annual Report, B.P. Koirala Memorial Cancer Hospital, Bharatpur, Nepal, 2010.
[5]  Sajid, MS., Tonsi, A., & Baig, MK. (2008). Health-related quality of life measurement. Int J Health Care Qual Assur. 21(4), 365-73.
[6]  Aaronson, NK., Ahmedzai, S., & Bergman, B., (1993). The European organization for research and treatment of cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology. J Natl Cancer Inst, 85, 365-376.
[7]  Ahmedzai, N. S., Bergman, B., Bullinger, M., Cull, A., & Duez, N.J. (1993). The European Organization for Research and Treatment of Cancer QLQ-30: a quality of life instrument for use in international clinical trials in oncology. J Natl Cancer Inst. 85(5), 365-76.
[8]  Testa, MA., & Simonson, DC. (2009). Assessments of quality-of-life outcomes. N Engl J Med 334, 835-4.
[9]  Maryam, Farooqui., Mohamed, Azmi. Hassali., Aishah, Knight., Asrul, Akmal. Shafie., Fahad, Saleem., Muhammad, Aslam. Farooqui., Hisham, Aljadhey.,(2013). Cross Sectional Assessment Health Related Quality of Life among Patients with Cancer in Malaysia. Asian Pacific Journal of Cancer prevention, 14 (5), 3017-3021.
[10]  Carlos, k. H. Wong., Cindy, l. K. Lam., jensen, t. C. Poon., & dora, l. W. Kwong. (2013).clinical indicators of depression among ambulatory cancer patients undergoing chemotherapy. Japanese journal of clinical oncology.10, 334-337.
[11]  World Health Organization, (2009). Focus in Priorities, WHO Report 2008, Available at (Retrieved on 26th June, 2011).
[12]  Zhen, Gou, J., Zheng, Y., Qian, JX., Gu, XQ. & Wang JJ. (2013). Study on factors affecting the quality of life to cancer patients at the community level in Shaghai. Zhonghua Liu Xing Bing Xue Za Zhi, 26 (100), 761-6 (Retrieved on 20th September, 2013).
[13]  Andrade, V., Sawada, N.O., & Barichello, E. (2011). Quality of life in hematologic oncology patients undergoing chemotherapy. Medical Journal of Malayasia, 66, (2) 84-87.
[14]  Bahar, Mahjoubi., Rezvan, -Mirzaei., and Leila, Zahedi-Shoolami.(2012). A cross-sectional survey of quality of life in colostomates. Health Qual Life Outcomes, 10,136.
[15]  Lim, G. (2011). Health related quality of life among patients with cancer. ASEAN J Psychiatry, 13 (1), 210-14.
[16]  Golden, Masika., Lena, Wettergren., Thecla, W. Kohi., & Louise von Essen (2012). "Health-related quality of life and needs of care and support of adult Tanzanians with cancer: a mixed-methods study" BioMed Central, 10, 90-94.
[17]  Donald, P. B., Gupta, D., and Edgar D. S. (2012). Predicting survival in prostate cancer: the role of quality of life assessment. Support Care Cancer. 20(6), 1267-1274.
[18]  Bottomley, A., & Therasse, p. (2005). Quality of life in patients undergoing systemic therapy for advanced breast cancer. Lancet oncol. 3, 620-628.
[19]  Johnsen A. (2009). Health related quality of life in a nationally representative sample of hematological patients. Eur. J. Haematol. 83 (92), 139-148. (PMC free article).
[20]  Priscilla, D. (2011). Quality of life among patients with Hematological cancer. Medical Journal of Malayasia, 66, (2).
[21]  Gupta, D., Braun, D.P., & Markman, M. (2013). Longitudinal health-related quality of life assessment: implications for prognosis in ovarian cancer.J Ovarian Res. 6, 17.
[22]  Heydarnejad, MS., Dehkordi, G., Hassanpour, D., & Dehkordi, K. (2011). Factors Affecting Quality of Life in Cancer Patients Undergoing Chemotherapy. African Health Science Journal, 11(2), 266-270. Http://Www.Ncbinlm.
[23]  Meyer, F., Fortin, A., Gelinas, M., Nabid, A., Brochet, F.,& Tetu, B. (2009). Health-related quality of life as a survival predictor for patients with localized head and neck cancer treated with radiation therapy. J Clin Oncol, 27, 2970-6.
[24]  Güner, P., Ishikhan V., Komurcu, S., Il, S., Ozturk, B., Arpaci, F., & Ozet, A. (2006). Quality of life and socio demographic characteristics of patients with cancer in Turkey. Oncology.
[25]  Damm K., Roeske, N., & Jacob, C. (2013). Health-related quality of life questionnaires in lung cancer trials: a systematic literature review. Health Econ Rev,13(3)11-15.
[26]  Zhou, De-ming., Chu, Jin-wei., & Cheng, Xiao-lin. (2004). Factors affecting the health-related quality of life in lung cancer patients; Measured by EORTC QLQ-C30 QLQ-L13. Turkish respiratory journal, 4(2), 61-66.
[27]  Rustoen, T., Moum, T., Wiklund, I. & Hanestad, BR. (2004). Quality of life in newly diagnosed cancer patients, Sigma Theta Tau International, Available at (Retrieved on 20th September, 2011).
[28]  Toyama, Yoichi., Seiya, Yoshiida., Ryota Saito., Hiroaki, Kitamura., Norimitsu Okui., Ryo, Miyake.,….Katsuhiko, Yanaga. (2013). Successful adjuvant bi-weekly gemcitabine chemotherapy for pancreatic cancer without impairing patients’ quality of life. BiomedCentral.
[29]  Nemati, M., Alhani, F.,,& Zandshahdi, R.(2013). 1st congress in quality of life. Tehran, Iran: Book of Abstracts. Quality of life in cancerous adolescences undergoing chemotherapy; p. 25.
[30]  Rustøen, T., & Hope, S. (2004). Quality of life, two central issues for cancer patients: a theoretical analysis. Cancer Nurs. 18, 355-361.
[31]  Esbensen, B. A., Osterlind, K., Roer, O. & Hallberg, R. (2004). Quality of life of elderly persons with newly diagnosed cancer. European Journal of Cancer Care (Engl).13(5), 443-53. Available at (Retrieved on 21st June, 2011).
[32]  Lee, H. L., Ku, N. P., Dow, W.j. & Pai, l. (2001). Factors related to quality of life in breast cancer patients receiving chemotherapy. Journal of nursing research, 9(3):57 - 68. (retrieved on 23rd june, 2013).
[33]  Gurm,BK., Stephen, J., & Mackenzie, G. (2008). Understanding Canadian Punjabi- speaking South Asian Women’s experience of breast cancer: qualitative study. Int J Nursing studies, 45, 266-76.
[34]  Van den Beuken (2009). Quality of life and non pain symptoms in Patients with Cancer. Journal of Pain and symptom Management, 38(2), 216-33.