American Journal of Clinical Medicine Research
ISSN (Print): 2328-4005 ISSN (Online): 2328-403X Website: Editor-in-chief: Dario Galante
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American Journal of Clinical Medicine Research. 2013, 1(2), 26-27
DOI: 10.12691/ajcmr-1-2-1
Open AccessCase Report

Ribosomal P Antibodies Preceding the Onset of Sle-A Case Report

Prashanth N C, Satyanarayana. N, T. AnilKumar, and Ravikumar. R

Pub. Date: April 02, 2013

Cite this paper:
Prashanth N C, Satyanarayana. N, T. AnilKumar and Ravikumar. R. Ribosomal P Antibodies Preceding the Onset of Sle-A Case Report. American Journal of Clinical Medicine Research. 2013; 1(2):26-27. doi: 10.12691/ajcmr-1-2-1


Systemic lupus erythematosus (SLE) is an autoimmune disorder characterized by the Production of auto antibodies directed against a variety of nuclear and cytoplasmic antigens. Auto antibodies to ribosomal Proteins are found in 15–30% of systemic lupus erythematosus (SLE) patients. Ribosomal P antibody is shown to predict SLE 1.7 years before clinical onset of SLE. This is a case of 28 year old female patient with a malar rash and nonspecific neurologic symptoms .The antibody profile showed that ANA ,anti- Ds dna and anti- Sm antibodies were negative but anti ribosomal P0 antibody was strongly positive(+++) at presentation. A strong clinical suspicion and careful follow-up helped in making a diagnosis of SLE over a period of nine months.

ribosomal P antibody SLE ANA

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