American Journal of Clinical Medicine Research
ISSN (Print): 2328-4005 ISSN (Online): 2328-403X Website: http://www.sciepub.com/journal/ajcmr Editor-in-chief: Dario Galante
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American Journal of Clinical Medicine Research. 2019, 7(2), 37-43
DOI: 10.12691/ajcmr-7-2-1
Open AccessArticle

Effectiveness of Castor Oil in Preventing Post-term Pregnancy in Low Resource Setting: A Randomized Controlled Trial

Okoro OS1, , Ugwu EO1, Dim CC1, Ozumba BC1, Nkwo PO1, Ajah LO1 and Okeke TC1

1Department of Obstetrics and Gynecology, University of Nigeria Teaching Hospital (UNTH), Enugu, Nigeria

Pub. Date: June 28, 2019

Cite this paper:
Okoro OS, Ugwu EO, Dim CC, Ozumba BC, Nkwo PO, Ajah LO and Okeke TC. Effectiveness of Castor Oil in Preventing Post-term Pregnancy in Low Resource Setting: A Randomized Controlled Trial. American Journal of Clinical Medicine Research. 2019; 7(2):37-43. doi: 10.12691/ajcmr-7-2-1

Abstract

Castor oil has long been used as a way of inducing labor and preventing post-term pregnancy. However, its safety and effectiveness has not been conclusive thereby necessitating the need for further studies. This article evaluated the effectiveness of single oral dose of castor oil at 40-41 weeks of gestation for prevention of post-term pregnancy, in a low resource setting. This was a randomized controlled trial of pregnant women attending antenatal care clinic at the University of Nigeria Teaching Hospital Enugu, Nigeria. The eligible participants were randomized into two groups; group A (intervention group) received oral castor oil (60mls) and group B (control group) did not receive castor oil. The intervention group had a lower incidence of post term pregnancy compared to the control group (18/105(17.1%) vs 44/106(41.5%), RR= 0.41, NNT= 4). The proportion of women requiring formal induction of labor with misoprostol or with oxytocin was significantly lower in the intervention group than in the control group (18/105 (17.1%) vs 44/106(41.5%), RR= 0.41, NNT= 4). The intervention group were less likely to have their labor augmented with oxytocin compare to the control 41/87(47.1%) vs 44/62(71.0%), RR 0.66, NNT 4). The route of delivery and the need for new born special care unit admission were similar in the two groups. There was no significant difference in the maternal complications due to castor oil in the two groups. Single oral dose of Castor oil administration significantly lowers the incidence of post- term pregnancy, without higher risk of maternal and/ or neonatal complications.

Keywords:
effectiveness castor oil preventing post-term pregnancy Enugu Nigeria

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