American Journal of Cardiovascular Disease Research
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American Journal of Cardiovascular Disease Research. 2022, 8(1), 37-48
DOI: 10.12691/ajcdr-8-1-4
Open AccessArticle

The Association between Sleep Duration and Coronary Artery Disease among American Adults in 2018

Jadthiel Oliva1, , Marina Shehata1, Asia Thomas1, Fred Rudensky1 and Prince Adu Amoako1

1Department of Research, American University of Antigua College of Medicine, Osbourn, Antigua & Barbuda

Pub. Date: August 16, 2022

Cite this paper:
Jadthiel Oliva, Marina Shehata, Asia Thomas, Fred Rudensky and Prince Adu Amoako. The Association between Sleep Duration and Coronary Artery Disease among American Adults in 2018. American Journal of Cardiovascular Disease Research. 2022; 8(1):37-48. doi: 10.12691/ajcdr-8-1-4


Context: Coronary artery disease (CAD) is the most prevalent form of heart disease in the United States. CAD has many modifiable risk factors, such as poor diet, smoking, and lack of exercise. Much like the factors above, short sleep duration is commonly reported by American adults. Objective: This study examines the association between sleep duration and CAD in American adults in 2018. Methods: We used data from adults 18 or older who participated in the 2018 Behavioral Risk Factor Surveillance System (BRFSS) cross-sectional study. The independent variable was sleep duration in hours (rounded up), and the categories were (≤5 hours, 6 hours, 7-8 hours, and ≥9 hours). The dependent variable was ever having MI, angina, or CAD as diagnosed by a healthcare professional. The frequency of CAD is presented as weighted sampling proportions. Uni- and multivariable logistic regression analysis were used to calculate unadjusted and adjusted odds ratio (OR) for CAD comparing selected characteristics and their corresponding 95% confidence interval (CI). STATA 16.1 was the statistical software we used. Results: Our sample included 421,983 participants. The reference value for sleep duration was between 7-8 hours. A higher percentage of participants who slept ≤5 hours (6.8% weighted) or ≥9 hours (7.5% weighted) experienced CAD as compared to those who slept 6 hours (4.1% weighted) or 7-8 hours (3.9% weighted). Logistic regression analysis indicates that individuals who slept ≤5 hours showed an increased odds of experiencing CAD based on OR 1.41 (95% CI 1.27-1.57) after adjusting for potential confounding variables. Furthermore, individuals who reported sleeping ≥9 hours also displayed increased odds of CAD (OR 1.21; 95% CI 1.03-1.42) after adjustment. The p-values for these categories were <0.001. Conclusion: Our study found that adults who slept 5 hours or less and those who slept 9 hours or more had an increased chance of experiencing coronary artery disease. This remained the case after adjusting for confounding variables such as age, sex, lifestyle, and comorbidities. These findings warrant further research regarding the association between sleep duration and coronary artery disease.

acute myocardial infarction sleep duration chronic sleep deprivation

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[1]  Daghlas I, Dashti HS, Lane J, Aragam KG, Rutter MK, Saxena R, Vetter C. Sleep Duration and Myocardial Infarction. J Am Coll Cardiol. 2019 Sep 10; 74(10): 1304-1314.
[2]  Chandola T, Ferrie JE, Perski A, Akbaraly T, Marmot MG. The effect of short sleep duration on coronary heart disease risk is mostificant among those with sleep disturbance: a prospective study from the Whitehall II cohort. Sleep. 2010 Jun; 33(6): 739-44.
[3]  Sabanayagam C, Shankar A. Sleep duration and cardiovascular disease: results from the National Health Interview Survey. Sleep. 2010 Aug; 33(8): 1037-42.
[4]  Nagai M, Hoshide S, Kario K. Sleep duration as a risk factor for cardiovascular disease- a review of the recent literature. Curr Cardiol Rev. 2010; 6(1): 54-61.
[5]  Buell P, Breslow L. Mortality from coronary heart disease in California men who work long hours. J Chronic Dis. 1960 Jun; 11: 615-26.
[6]  Laugsand, L., Vatten, L., Platou, C. and Janszky, I., 2011. Insomnia and the Risk of Acute Myocardial Infarction. Circulation, 124(19), pp.2073-2081.
[7]  Watson NF, Badr MS, Belenky G, Bliwise DL, Buxton OM, Buysse D, Dinges DF, Gangwisch J, Grandner MA, Kushida C, Malhotra RK, Martin JL, Patel SR, Quan SF, Tasali E. Recommended amount of sleep for a healthy adult: a joint consensus statement of the American Academy of Sleep Medicine and Sleep Research Society. J Clin Sleep Med 2015; 11(6): 591-592.
[8]  Pierannunzi C, Hu SS, Balluz L. A systematic review of publications assessing reliability and validity of the Behavioral Risk Factor Surveillance System (BRFSS), 2004-2011. BMC Med Res Methodol. 2013 Mar 24; 13: 49.
[9]  Centers for Disease Control and Prevention. Behavioral Risk Factor Surveillance System.
[10]  Hirshkowitz M, Whiton K, Albert SM, Alessi C, Bruni O, DonCarlos L, Hazen N, Herman J, Katz ES, Kheirandish-Gozal L, Neubauer DN, O'Donnell AE, Ohayon M, Peever J, Rawding R, Sachdeva RC, Setters B, Vitiello MV, Ware JC, Adams Hillard PJ. National Sleep Foundation's sleep time duration recommendations: methodology and results summary.