American Journal of Biomedical Research
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American Journal of Biomedical Research. 2014, 2(1), 11-15
DOI: 10.12691/ajbr-2-1-3
Open AccessArticle

Sero-Prevalence of Hepatitis B and Hepatitis C Virue Co-Infection among Pregnant Women in Nigeria

A.J Esan1, , C.T. Omisakin1, T. Ojo-Bola2, M.F Owoseni1, K.A Fasakin1 and A.A Ogunleye3

1Hematology Department, Federal medical Centre, Ido-Ekiti, Nigeria

2Medical Microbiology Department, Federal Medical Centre, Ido-Ekiti, Nigeria

3Ondo State General Hospital, Okitipupa, Nigeria

Pub. Date: February 09, 2014

Cite this paper:
A.J Esan, C.T. Omisakin, T. Ojo-Bola, M.F Owoseni, K.A Fasakin and A.A Ogunleye. Sero-Prevalence of Hepatitis B and Hepatitis C Virue Co-Infection among Pregnant Women in Nigeria. American Journal of Biomedical Research. 2014; 2(1):11-15. doi: 10.12691/ajbr-2-1-3


This study was carried out to determine sero-prevalence of hepatitis B and hepatitis C virus co-infection among pregnant women. Viral hepatitis during pregnancy is associated with high risk of maternal complications; infections with Hepatitis B virus (HBV) or the Hepatitis C virus (HCV) are public health problems. Worldwide, there are about 350 million HBV carriers and 130 to 170 million people infected with HCV. The presence of HBV and HCV was determined using third-generation enzyme immunoassay (EIA), reactive samples were further confirmed using enzyme linked immune sorbent assay (ELISA) (Bio-Rad, France). Age group 26-30 and 31-35 had highest frequency of 240 (36.98%) and 206 (31.74%) respectively in HBV and HCV. Sero prevalence of HBV and HCV were 44 (6.78%) and 9 (1.39%) respectively. Prevalence of HBV and HCV co-infection was 1 (0.15%) in age group 31-35. Proper management of maternal hepatitis during the prenatal phase ensures better outcomes in the infant, therefore screening of pregnant women for hepatitis B and C virus are necessary in order to identify those neonates at risk of transmission.

Hepatitis B virus Hepatitis C virus transmission

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