Enviro-economic Synthesis, Characterization and Antibacterial Study of O-Alkyl or O-Aryl Trithiophosphates of Cadmium

Kamiya Mundra¹ and Alok Chaturvedi^1,

¹Synthetic and Surface Science Laboratory, Department of Chemistry, S.P.C. Govt. College, Ajmer 305001, Rajasthan, India

Cite this paper:
Kamiya Mundra and Alok Chaturvedi. Enviro-economic Synthesis, Characterization and Antibacterial Study of O-Alkyl or O-Aryl Trithiophosphates of Cadmium. Applied Ecology and Environmental Sciences. 2020; 8(4):174-178. doi: 10.12691/aees-8-4-5

Abstract

Cadmium (II) O-alkyl or O-aryl trithiophosphate of the type Cd[KS(S₂)POR]₂ (where R= Me, Et, Prⁱ, Buⁱ, Ph, CH₂Ph) have been synthesized by an environmentally harmless, efficient and quick smooth way from the reaction of cadmium chloride and dipotassium salt of O-alkyl or O-aryl trithiophosphates in 1:2 molar ratio. They are synthesized by solvent free conditions and microwave assisted procedure. These derivatives are yellow colour solids, insoluble in common organic solvents but are soluble in DMSO, DMF and pyridine. These have been characterized by elemental analysis, molecular weight determinations and spectroscopic(IR, ¹H and ³¹P NMR) studies. On the basis of them square planar geometry has been proposed for these derivatives. The newly synthesized complexes show effectiveness against gram positive and gram negative bacteria and a comparative study of antibacterial effect of synthesized compounds with standard drugs has also been investigated.

Keywords:
cadmium chloride dipotassium salts of O-alkyl or O-aryl trithiophosphates solvent free conditions microwave assisted procedure antibacterial activity

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